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All Journal Majalah Obat Tradisional Viva Medika: Jurnal Kesehatan, Kebidanan dan Keperawatan JPP Jurnal Kesehatan Poltekkes Palembang BERNAS: Jurnal Pengabdian Kepada Masyarakat Jurnal ABDIKU Jurnal Ilmiah Pamenang (JIP) Jurnal Pengabdian kepada Masyarakat Nusantara Journal of Pharmaceutical and Health Research Jurnal Pengabdian Masyarakat Abdimas Madani Jurnal Pengabdian kepada Masyarakat Health Media Jurnal EduHealth INDRA: Jurnal Pengabdian kepada Masyarakat International Journal of Islamic and Complementary Medicine Jurnal Akuntansi dan Keuangan Jurnal Pengabdian Masyarakat Bidang Sains dan Teknologi Journal of Innovation Research and Knowledge Jurnal Pengabdian dan Pengembangan Masyarakat Indonesia PEKAT : Jurnal Pengabdian Kepada Masyarakat Journal Prima Health Science The Health Researchers Journal Journal of Medical Laboratory in Infectious and Degenerative Diseases Sadewa: Jurnal Pengabdian Masyarakat
nafisah isnawati
Program Studi Farmasi, Fakultas Ilmu Kesehatan, Universitas Dr. Soebandi
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Profile of the combination of two oral anti-diabetes drugs in patients diabetes melitus at Citra Husada hospital Jember Miatuz Zaqia; Mayasari, Shinta; Nafisah Isnawati
Jurnal EduHealth Vol. 15 No. 01 (2024): Jurnal eduHealt, Edition January - March, 2024
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Diabetes melitus (DM) is a group of diseases with characteristic hyperglycemia that occurs due to impaired insulin secretion, insulin action, or both. The International Diabetes Federation (IDF) notes that Indonesia has the country with the fifth most significant number of diabetics in the world, with 19.5 million Indonesians aged 20-79 years suffering from the disease. Therefore this study aims to determine the profile of the use of a combination of two classes of oral hypoglycemic drugs in type 2 DM patients at Citra Husada Hospital in 2022. This research is a descriptive study with retrospective data collection. The population in this study were all outpatients diagnosed with Type 2 DM at Citra Husada Hospital in 2022. Source of medical record data. The number of samples using a population of 100 patients in the outpatient installation at Citra Husada Hospital. This study used a total sampling technique which is a sampling technique that uses all members of the population. Data analysis used univariate analysis in the form of proportions. Research results show that 100 samples are included in the inclusion criteria. Results of the study Most of the patient characteristics were female (61%), age range 56-65 years (39%), and hypertension co-morbidities (33%). The results of a combination study of two classes of oral anti-diabetes drugs, namely the sulfonylurea group (glimepiride at a dose of 3 mg, the drug frequency is taken once a day every morning with the thiazolidinedione group (pioglitazone at a dose of 30 mg, the drug frequency is taken once a day during the day) (35%). The most common used of combinations of two classes of oral anti-diabetes drugs in patients Diabetes melitus at Citra Husada Hospital are sulfonylureas and thiazolidinediones
Cross-Sectional Study on Knowledge and Attitudes of Nonhealth Students Towards The Use of Antibiotics in Bangkalan Regency April Nuraini; Nafisah Isnawati; Ratri Rokhani
Viva Medika Vol 17 No 3 (2024)
Publisher : Universitas Harapan Bangsa Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35960/vm.v17i3.1594

Abstract

Antibiotics are drugs to kill bacteria or slow their growth. Antibiotics should be used at the doctor's clinical discretion and administered to the patient on prescription. The purpose of this study was to determine the relationship of unhealthy student knowledge level to the attitude and behavior of antibiotic use. Descriptive analysis research method with cross sectional approach on unhealthy students in Bangkalan Regency. Sampling was done by purposive sampling technique with questionnaire. The number of samples was 96 respondents conducted in March-May 2024. Analysis of bivariate and mulitivariate data. Data analysis with logistic regression. The results of the study stated that most of the non-health students in Bangkalan have enough knowledge in the category (40.2%), have enough attitude in the category (43.3%) and enough behavior (48.4%). The relationship of students ' level of knowledge to the attitude and behavior of antibiotic use using spearman correlation test that is sig value of 0.000 (<0.05) shows the relationship between the level of knowledge with the attitude and behavior of antibiotic use
HUBUNGAN KEPATUHAN PENGGUNAAN OBAT ANTIHIPERTENSI DENGAN TEKANAN DARAH PADA PASIEN HIPERTENSI DI PUSKESMAS X di KABUPATEN JEMBER isnawati, nafisah; Khamim, Nur; H, Prasetyo
The Health Researcher's Journal Vol. 1 No. 03 (2024): The Health Researchers Journal
Publisher : The SDGS Forum Communication

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.00000/2gft5n48

Abstract

Hipertensi adalah salah satu penyakit tidak menular yang saat ini menjadi prioritas kesehatan secara global. menurut data nasional, Jawa Timur menjadi salah satu provinsi dengan tingkat hipertensi tertinggi kedua pada tahun 2020 dengan prevalensi 36,32%. Tingginya prevalensi hipertensi disebabkan oleh rendahnya kepatuhan pasien terhadap penggunaan obat antihipertensi. Mempertahankan target tekanan darah merupakan tujuan utama dari pengobatan hipertensi. penelitian ini dilakukan untuk mengetahui hubungan antara kepatuhan penggunaan obat antihipertensi dengan tekanan darah pada pasien hipertensi di Puskesmas X Kabupaten Jember. Penenlitian ini merupakan penelitian kuantitatif yang menggunakan metode penelitian observasional dengan mengumpulkan data melalui pengisian kuisioner oleh responden memiliki tingkat kepatuhan tinggi yaitu 24 orang (52%0 dan tingkat kepatuhan rendah yaitu 22 orang (48%). Pada tekanan darah responden termasuk dalam ketagori pra=hipertensi (120-139 mmHg) sebanyak 14 orang (30%). Dari hasil penelitian di simpulkan bahwa terdapat hubungan antara kepatuhan dengan tekanan darah pada penderita hipertensi di Puskesmas X Kabupaten Jember
OPTIMASI FORMULA HANDSANITIZER MINYAK BUNGA CENGKEH (Syzygium aromaticum): EVALUASI SIFAT FISIK DAN UJI ANTIBAKTERI TERHADAP Staphylococcus aureus : FORMULATION OPTIMIZATION OF CLOVE ESSENTIAL OIL HAND SANITIZER (Syzygium aromaticum) : PHYSICAL PROPPERTY EVALUATION AND ANTIBACTERIAL TESTING AGAINST Staphylococcus aureus Nafisah Isnawati; Pujiastuti, Atikah
Jurnal Ilmiah Pamenang Vol. 6 No. 1 (2024): Jurnal Imiah Pamenang (JIP)
Publisher : Stikes Pamenang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53599/jip.v6i1.210

Abstract

Abstrak   Penyakit infeksi bisa ditularkan melalui perantara tangan maka dari itu, salah satu cara untuk membersihkan tangan secara efisien, efektif dan aman adalah dengan menggunakan hand sanitizer yang mengandung bahan aktif dari alam. Kandungan utama dalam minyak atsiri bunga cengkeh adalah senyawa eugenol sebesar 72-90%. Senyawa eugenol bunga cengkeh merupakan senyawa antibakteri mampu menghambat pertumbuhan bakteri. Penelitian ini bertujuan untuk mengetahui untuk mengetahui mutu fisik yang meliput uji organoleptis, uji pH, uji homogenitas, uji daya sebar, uji daya lekat, uji viskositas dan uji aktivitas antibakteri sediaan terhadap bakteri Staphylococcus aureus. Metode penelitian ini bersifat eksperimental dimana dilakukan formulasi sediaan dengan konsentrasi minyak atsiri bunga cengkeh 4%, 6%, 10%. Evaluasi mutu fisik sediaan emulgel  meliputi uji organoleptis, uji pH, uji homogenitas, uji daya sebar, uji daya lekat, uji viskositas dan uji aktivitas antibakteri terhadap bakteri Staphylococcus aureus dengan metode difusi cakram. Hasil penelitian menunjukkan bahwa ketiga formulasi menghasilkan emulgel yang homogen, lembut, kental, berbau khas cengkeh, berwarna bening, putih tulang, putih kekuningan dan kuning langsat. Mutu fisik homogenitas, daya sebar, daya lekat sediaan emulgel hand sanitizer minyak atsiri bunga cengkeh memenuhi persyaratan mutu fisik sediaan namun untuk uji pH hanya F3 yang memenuhi persyaratan uji mutu pH dan sediaan emulgel F1 dan F1 mempunyai potensi daya hambat sedang, dan F3 memiliki potensi yang paling kuat dalam membunuh bakteri. Abstract   Infectious diseases can be transmitted through hands, therefore one way to clean hands efficiently, effectively and safely is to use an emulgel hand sanitizer which contains active ingredients from nature. The main content of clove flower essential oil is eugenol compound of 72-90%. Clove flower eugenol is an antibacterial compound that can inhibit bacterial growth. This study aims to determine whether clove flower essential oil can be formulated into an emulgel hand sanitizer preparation, to determine the physical quality which includes organoleptic test, pH test, homogeneity test, spreadability test, adhesion test, viscosity test and antibacterial activity test of the preparation against bacteria Staphylococcus aureus. This research method is experimental in nature where formulations are made with clove flower essential oil concentrations of 4% (F1), 6% (F2), 10% (F3) and base control (F0). Evaluation of the physical quality of emulgel preparations included organoleptic tests, pH tests, homogeneity tests, spreadability tests, adhesion tests, viscosity tests and antibacterial activity tests against Staphylococcus aureus bacteria. The results showed that the three formulations produced an emulgel that was homogeneous, soft and viscous, had a distinctive clove odor, was clear in color, white in bone, yellowish white and olive. The physical quality of homogeneity, dispersion, adhesive power of clove essential oil hand-processed clove essential oil met the physical quality requirements of the preparation but for the pH test only F3 met the pH quality test requirements and emulgel preparations F1 and F1 have moderate inhibitory potential, while F3 has the strongest potential in killing bacteria.
Pelatihan Pembuatan Produk Minuman Kesehatan Berbasis Bahan Alam dan Penyuluhan Regulasi Perijinan SPP IRT Nafisah Isnawati; Shinta Mayasari; Khrisna Agung; Endang Lifchatullaillah; Helmalia, Helmalia
ABDIKAN: Jurnal Pengabdian Masyarakat Bidang Sains dan Teknologi Vol. 2 No. 4 (2023): November 2023
Publisher : Yayasan Literasi Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55123/abdikan.v2i4.2481

Abstract

The empirical utilization of plants as traditional medicine is still limited to making herbal decoctions which are rather long and on average taste bitter. The development of the utilization from medicinal plants in the form of health drinks that are easy to consume and taste acceptable to the public is still very low. Plant materials that are widely used include kencur in the form of herb beras kencur, temu lawak in the form of herb temu lawak. Therefore, this activity is to improve the health status for the community and increase the economic independence of the community by entrepreneurship with health drinks that are made from natural ingredients with innovative processing. The method that used in is counseling and hands-on practice of making, labeling products. The target audience is people whose daily activities are small entrepreneurs. The results obtained from this activity are increasing knowledge about the utilization of natural ingredients as health drinks, knowledge of SPP-IRT licensing regulations, and processing practices for making, packaging and labeling health drink products in the form of instant beras kencur, instant temu lawak and temu lawak syrup that have worth to sell.
EFFECT OF DRYING TEMPERATURE AND TIME ON TABLET FORMULATION OF MORINGA LEAF (Moringa oleifera) EXTRACT WITH WET GRANULATION METHOD USING FLUID BED DRYER Isnawati, Nafisah; Zulfatul Maskuriah, Dian; Wicaksono, Yudi
International Journal of Islamic and Complementary Medicine Vol. 2 No. 2 (2021): International Journal Islamic Medicine
Publisher : International Islamic Medicine Forum

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (224.529 KB) | DOI: 10.55116/IJIM.V1I1.27

Abstract

Moringa leave is medicinal plant type that often used by society. Flavonoid and saponin are the content of moringa leave which have benefit as immunomodulator. Moringa leave using can be more practical and easy to used by making as pharmaceutical preparation. Drying temperature and time have a great effect on the physical properties of granule and tablet manufacturing. The objective of this research is to find out the effect of drying temperature and time on the physical-mechanical properties of granule and physical-disintegrant properties of moringa leave extract tablet by wet granulation method. The research method using experimental laboratory methods is correlational (causation). Moringa leave extract tablet was made with 6 formulations by various drying temperature and time. Drying temperature and time which used are FI 40°35', FII 50°35', FIII 60°35', FIV 40°45', FV 50°45', FVI 60°45'. Each formulation was carried out physical properties test of granule and tablet. The data obtained were compared to the pharmacopoeai and other literature and carried out statistical test. In order to know the effect of temperature using Shapiro-Wilk test, then continued ANOVA test, while for the effect of time using independent sample T-test with 95% confidence level, then continued Turkey-HSD test. The result of the test showed that the differences of drying temperature and time have effect on the physical properties of tablet, namely, hardness, brittleness, and disintegration time. The increasing of drying temperature and time are able to reduce the brittleness, increase the hardness, and prolong disintegration time of tablet.  
Co-Authors Abdullah Azzam Mubarok Achmadan Rizki Trisnawan Adek Intan Suryaning Rahayu Adi Rama Agung , Khrisna Agung C., Khrisna Agustin, Nanda Nelly Alfajri, Irza Aliyah Purwanti Ana Karunia Angga Dwi Rofiqil Anggraeni, Lutvi Anisa Agustina April Nuraini Aril Alifia Salsabila Athallah, Naufal Danipratiwi, Sidta Putrirachman Darotin, Rida Dewi Lufitasari Dhina Ayu Susanti Diah Yuli Pangesti Dina Tria Dina Tria Dina Trianggaluh Dina Trianggaluh Fauziah Dina Trianggaluh Fauziah Dwi, Jacinta Dzikri, Fachrizal Endang Lifchatullaillah Endang Lifchatullaillah Fachrizal Dzikri Fathmasari, Tiara Fatika, Diva Aulia Nur Fitria Meliana Putri Florentinus Dika Octa Riswanto Friskila Nenobesi H, Prasetyo HELMALIA HELMALIA, HELMALIA Helmalia Shintawati Hidayatul Wahdah Illa Faizah Nur’Ain Irza Alfajri Iski Weni Pebriarti Kenny Raul Supaat Khafifah Indar Purwaningsih Khamim, Nur Khofifah Amini Khoirun N., Hilda Khrisna Agung Khrisna Agung Cendekiawan Kustin kustin uds Lina Winarti lindawati setyaningrum Lufitasari, Dewi M. Rofik Usman Mega Fitriya Purnama Dewi Miatuz Zaqia Mubarok, Abdullah Azzam Natasya, Leanasta Ina Naufal Athallah Noval Kurniawan Nufus, Galuh Maulidatun Nur Azizah Perdani Puteri Syahuri Syahuri Nuraini, April Nurul Izmi Agustina Pangesti, Yuli Perdana, Rastra Airlangga Poppy, Leony Rayvina Pujiastuti, Atikah Purwaningsih, Khafifah Indar Rahayu, Adek Intan Suryaning Rastra Airlangga Perdana Ratri Rokhani Rayyan Sabil Prayoga Regeena Juia Yasmine Rindiani Safitri Rohma, Hilda Khoirunnisa Rokhani, Ratri Rosita Bahadun Safitri, Rindiani Shinta Mayasari Shinta Mayasari Sholihatil Hidayati Sidta Putrirachman Danipratiwi Silvia Yunani Trisnani Siti Rosyida Sivi Richa Marini Stivaniyanti Atmanegara Supaat, Kenny Raul Susanti, Dhina Ayu Thomas Adhi Tamsyah Tiara Fathmasari Trisnani, Silvia Yunani Trisnawan, Achmadan Rizki Tsamarotu Qobi Imamah Utomo, I,R1, Utomo, I,R1 Wahdah, Hidayatul Yudi Wicaksono Yunitasari, Risky Zakiyah Tur Rohmah Zidni Nuris Yuhbaba Zulfatul Maskuriah, Dian