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All Journal Jurnal Veteriner Indonesia Medicus Veterinus
Anak Agung Gde Arjana
Laboratorium Farmasi Veteriner, Fakultas Kedokteran Hewan Universitas Udayana, Jl. PB. Sudirman, Denpasar, Bali
Medicine & Pharmacology Veterinary

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Journal : Jurnal Veteriner

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Studi Patologi Kejadian Cysticercosis pada Tikus Putih I Ketut Berata; Anak Agung Gde Arjana; I Wayan Sudira; I Made Merdana; I Ketut Budiasa; Ida Bagus Made Oka
Jurnal Veteriner Vol 11 No 4 (2010)
Publisher : Faculty of Veterinary Medicine, Udayana University and Published in collaboration with the Indonesia Veterinarian Association

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Abstract

Rats are commonly used as animal model in pathological and reproduction research, butunfortunately they are often infected with cysticercosis. The objective of this research was to determinethe pathological changes the of the rats (Rattus novergicus) tissues affected with cysticercus. Thisresearch using 24 of female rats. They were adapted to a new environment for a week and the feeding andwater were provided ad libitum. At the end of adaptation period rats were necropsied and the visceralorgans were examined for pathological changes especially the present of cysticercosis. The liver and kidneyof each rat were soaked in 10% phosphate buffered formalin. Following dehydration process, tissue wereembedded in paraplast, cut at 5 micron and stained with Harris hematoxylin eosin (HE). The resultshowed that 8 of 24 rats were affected by cysticercosis on the liver. The histopathological changes werenecrotic lesions and eosinophylic cells infiltration around the cysticercosis lesion. The results showed that8 of 23 rats were affected by cysticercosis. The presence of necrosis and cells inflammation could interferethe results of the study when such a rats are used. It is therefore necessary to screen rats for cysticercosis.
Co-Authors Anak Agung Sagung Istri Pradnyantari Anak Agung Sagung Kendran Cok Krishna Pemayun DWI SURYANTO Gde Jasmara Muda I GEDE ENDRA KUSUMA I Ketut Berata I Made Dwinata I Made Merdana I Wayan Sudira Ida Bagus Made Oka Jayawardhita, Anak Agung Gde Ketut Budiasa Lusiana Flora Ndagu Made Beratha Mukti Muh Amiruddin Nesia Masniari Helena Sibarani Ni Ketut Suwiti Ni Luh Eka Setiasih Ningsih, Adriati Pangesti, Thiara A. Rio Fadly Sihombing Samsuri Samsuri ST Kholifah Nor Azizati Suandhika, Putu Teja, Putu Tessa Hariys Septianda