Article Per Year (5 Year)
p-Index From 2021 - 2026
0
P-Index
This Author published in this journals
All Journal Althea Medical Journal Paediatrica Indonesiana
Ryadi Fadil
Unknown Affiliation
Health Professions Medicine & Pharmacology

Published : 4 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search
Journal : Paediatrica Indonesiana

 1 
Association between age and serum ferritin level with bone age deficit in children with thalassemia major Sri Hastuti Andayani; Nanan Sekarwana; Ryadi Fadil
Paediatrica Indonesiana Vol 48 No 1 (2008): January 2008
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (317.675 KB) | DOI: 10.14238/pi48.1.2008.33-6

Abstract

Background Multiple blood transfusions in thalassemia patientslead to iron overload in bone tissue. Iron overload can bedetermined by serum ferritin measurement. Several studies haveevaluated association between serum ferritin level and growth,but without bone age examination.Objective To determine the association between age and serumferritin level with bone age in children with thalassemia major.Methods This study was conducted at Hasan Sadikin HospitalBandung during March-May 2007. We performed physicalexamination, serum feritin measurement, and bone ageexamination. Data were analyzed with x 2 to determine associationbetween variables. The association between age and serum ferritinlevel with bone age deficit was analyzed with regression logisticmodel.Results Subjects consisted of 49 patients with thalassemia major.All subjects had bone age deficit. Most boys were in age group of>10 years and had bone age difference >36 months, while mostgirls were <10 years and had bone age difference <36 months.Subjects with bone age difference <36 months mostly had serumferritin level <5,000 ng/dL, while most subjects with bone agedifference >36 months had serum ferritin level =5,000 ng/dL.This was statistically significant (x 2 =4.573, P=0.032). There wasassociation between age and bone age deficit (OR=13.461, 95%CI 3.199;56.640), but not with serum ferritin level (OR= 2.199,95% CI 0.532;9.095).Conclusion In thalassemic children, bone age deficit is associatedwith age, but not with serum feritin level.
Thyroxine and thyroid stimulating hormone levels in under-five severe malnourished children Shelvi H. Tamzil; Ryadi Fadil; Diet S. Rustama; Melinda D. Nataprawira
Paediatrica Indonesiana Vol 43 No 2 (2003): March 2003
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi43.2.2003.42-5

Abstract

Background In Indonesia, protein energy malnutrition (PEM) inchildren is still a health problem. Malnourished children will havegrowth and development disruption, which is not only caused bynutritional factor, but might be associated with endocrine system,such as thyroid hormone metabolism. Hypothyroidism or thyroidhypofunction could be happened in malnourished children.Objective The purpose of this study was to assess thyroxine (T4)and thyroid stimulating hormone (TSH) levels in under-five severemalnourished children.Methods This was a descriptive study with cross sectional design.Subjects were all under-five severe malnourished childrenbased on nutritional evaluation in August 2001 done by local healthcare workers in Andir District, Bandung. Severe malnutrition wasdefined as weight for age less than -3SD (W/A <-3SD).Results There were 42 subjects who fulfilled inclusion criteria, aged11-57 months, five of them showed clinical manifestation of marasmus.The T4 levels of the 41 subjects were still in normal limitsand within the range of 4.5-11.2 mg/dl. Thirty-nine subjects hadnormal TSH levels, ranged from 0.9 to 5.0 mlU/ml, and 2 subjectsshowed increased TSH levels of 6.8 and 7.6 mlU/ml, respectively.Reduced T4 and TSH levels of 3.93 mg/dl and 0.2 mlU/ml, respectivelywere detected in one subjectConclusion In general, the T4 & TSH levels were still normal,with only one subject (2%) showed low levels of T4 & TSH.
Co-Authors Diet S. Rustama Hadyana Sukandar Lola Ilona Melinda D. Nataprawira Nanan Sekarwana Prema Sharlini Rinasyah Ganesh Shelvi H. Tamzil Sri Hastuti Andayani