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Journal : Britain International of Exact Sciences Journal (BIoEx Journal)

Fixed Drug Eruption: Case Report Azhari Gani; Muhammad Jailani
Britain International of Exact Sciences (BIoEx) Journal Vol 2 No 3 (2020): Britain International of Exact Sciences Journal, September
Publisher : Britain International for Academic Research (BIAR) Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/bioex.v2i3.310

Abstract

Drug allergy is characterized by hypersensitivity reactions to pharmacological agents, having an immune mechanism of development. In these reactions antibody and/or activated T cells are directed against medications or their metabolites. This problem is rather urgent for practical healthcare, as over 7% of people suffer from drug allergy. A 54-year old male presented at the emergency room Hospital Zainoel Abidin with redness and swelling of the bodies of a burning sensation, itching pain. In the detailed anamnesis taken from the patient, it was learned that 1 days previously he had consulted a nurse with the fever and 60 min after examination had been prescribed with acid mefenamic. Hypersensitivity immune reactions to medications, according to the present concepts, are divided into immediate reactions (within 1–6 h after starting the preparation manifesting with various forms—from mild to life-threatening symptoms of anaphylaxia), or delayed reactions (several hours to several days after the offending medication is started, manifesting clinically with exanthemas in the majority of cases). Drug allergy should be prevented.Steps to prevent allergic drug reactions include (1) a careful history to determine host risk factors, (2) avoidance of cross-reactive drugs, (3) use of predictive tests when available, (4) proper and prudent prescribing of drugs (especiallyantibiotics) that are frequently associated with adverse reactions,(5) use of oral drugs when possible, and (6) documentation of drug allergy in the patient’s medical record.
One-Step Urethroplasty in Recurrent Chordee on Scrotal Hipospadia Muhammad Jailani
Britain International of Exact Sciences (BIoEx) Journal Vol 2 No 3 (2020): Britain International of Exact Sciences Journal, September
Publisher : Britain International for Academic Research (BIAR) Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/bioex.v2i3.311

Abstract

Hypospadia is genitalia externa congenital anomaly in male. Recurrent chordee is one of most complication often happen in hypospadias correction. One-step urethroplasty in recurrent chordee is very challenging due to formed massive fibrosis. Correction surgery goals is to release chordee and moving meatus urethra externa to glans tip, and could be done by one-step or two-step. We report patient, 13 years old boy came with chief complain urinate from scrotal region. Patient was diagnose with scrotal hypospadia. Patient done chordee excision previously, but penis still not straight. Then, we perform one-step urethroplasty rechordee excision with local flap. Patient was follow-up one week postoperative, wound in good condition, and dehiscent wasn’t found. Urinary catheter released after three weeks. Evaluation also done in one month postoperative, and found no fistel. One-step urethroplasty rechordee excision was perform in scrotal hypospadi with local urethroplasty flap technique. Evaluation from beginning until two months postoperative found no fistel and urinate in straight line.