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Harbanu H Mariyono
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Medicine & Pharmacology

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Journal : journal of internal medicine

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ADVERSE DRUG REACTION Mariyono, Harbanu H; Suryana, Ketut
journal of internal medicine Vol. 9, No. 2 Mei 2008
Publisher : journal of internal medicine

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Abstract

There are lots of new drugs that made for therapy, prevent and even as a diagnostic tools. Beside the desired effect therewere also undesired effect that can occur when managing patient with drugs which then we call adverse drugs reaction. Anadverse reaction to a drug has been defined as any noxious or unintended reaction to a drug that is administered in standard dosesby the proper route for the purpose of prophylaxis, diagnosis, or treatment. Adverse drug reaction can be devided in two groups,which is reactions than can occur on everyone and the ones that can only occur on susceptible ones. One of the adverse drugreaction is drug allergy. History taking is the most important thing on diagnosing drug allergy, one that can help was Naranjosscore. We can run few more test to defined the type of Adverse Drug Reaction. For managing patient with adverse drug reaction,we have to avoid drugs that induce the reaction, premedication and also desensitisation.
GAGAL JANTUNG Mariyono, Harbanu H; Santoso, Anwar
journal of internal medicine Vol. 9, No. 1 Januari 2008
Publisher : journal of internal medicine

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Abstract

Heart failure were the end stage of all heart disease and the cause of the increasing morbidity andmortality among patient. Almost five percent from all inhospital patient were heart failure. Heart failure hasbeen defined as the failure of the heart to pump blood to systemic. It can be classify into acute, acutedecompensated and chronic heart failure. New York Heart Association, Stevenson, Forrester have madeclassification based on the clinical symptoms. All cardiac problems can ended into heart failure, thepathogenesis was very complex including renin-angiotensin-aldosteron system, neurohormonal, sympatic nervesystem, nattriuretic peptide, and others. Twelve leads ECGs, echocardiography, chest x-rays, blood chemistries,catheterisation can help us diagnose patient with heart failure. Management of heart failure consist ofmanagement of acute and chronic heart failure, non drugs management, drugs and even an invasive treament.
Co-Authors Anwar Santoso Ketut Suryana