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Ponpon Idjradinata
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Health Professions Medicine & Pharmacology

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The risk factors for febrile neutropenia during chemotherapy in children with malignancy Rini Sulviani; Ponpon Idjradinata; Harry Raspati
Paediatrica Indonesiana Vol 47 No 2 (2007): March 2007
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (369.756 KB) | DOI: 10.14238/pi47.2.2007.83-7

Abstract

Background Febrile neutropenia is the most common side effectof myelosuppressive chemotherapy. It is important to identify itsrisk factors to decrease the morbidity and mortality of febrileneutropenia.Objective To identify whether age, type of malignancy, phase anddose of chemotherapy, nutritional status, and absolute neutrophylcount are risk factors for febrile neutropenia.Methods A hospital-based case control study was conducted atHasan Sadikin Hospital from June 2000 to July 2005. Data wascollected from medical records. The case group consisted ofchildren with malignancy who received chemotherapy andsuffered from febrile neutropenia, while the control groupconsisted of children without febrile neutropenia. Chi square andlogistic regression analysis were performed to analyze data usingSPSS for Windows version 13.0.Results Eighty-seven cases and 94 controls were evaluated.Analysis showed that malignancy type i.e, hematologicmalignancy, chemotherapy phase, and absolute neutrophyl countmight be the risk factors for febrile neutropenia (OR=4.6, 95%CI 1.3;16.7, P=0.019; OR=8.1, 95% CI 2.2;30.5, P=0.002; andOR=1.0, 95% CI 1.003;1.007, P <0.001, respectively), while age,chemotherapy dose, and nutritional status might not be the riskfactors (median 60, range 6-144, P=0.342; OR=1.9, 95% CI0.8;4.8, P=0.129; and P=0.798, respectively).Conclusion Hematologic malignancy, induction phase ofchemotherapy, and absolute neutrophyl count =250/mm 3 are therisk factors for febrile neutropenia in children with malignancywho received chemotherapy.
A Case of Perforation of the Gallbladder in Association with Typhoid Fever Ponpon Idjradinata; E. Suroto-Hamzah; Sugiri Sugiri
Paediatrica Indonesiana Vol 14 No 1-2 (1974): January - February 1974
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (510.295 KB) | DOI: 10.14238/pi14.1-2.1974.21-24

Abstract

The purpose of this paper is to report a case of rupture of gallbladder in a child in association with typhoid fever.
Co-Authors E. Suroto-Hamzah Harry Raspati Rini Sulviani Sugiri Sugiri