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All Journal Biology, Medicine, & Natural Product Chemistry YARSI Medical Journal Majalah Kesehatan Pharmamedika Science Midwifery Reswara: Jurnal Pengabdian Kepada Masyarakat Junior Medical Journal Cerdika: Jurnal Ilmiah Indonesia Eduvest - Journal of Universal Studies Jurnal Ruhul Islam
Aan Royhan
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Journal : Junior Medical Journal

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Literature Review : The Effects of Antioxidant Saponins in Herbal Plants on Testicular Histology of Rats with Diabetes Mellitus and The Review of Islamic Perspective Jean Kharismatik Persada; Etty Widayanti; Aan Royhan
Junior Medical Journal Vol 1, No 8 (2023)
Publisher : Junior Medical Journal

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33476/jmj.v1i8.3313

Abstract

Introduction: Diabetes mellitus is a metabolic disorder. Diabetes mellitus can cause a decrease in sperm count, sperm motility, testosterone hormone, erectile ability, libido and testicular weight. Antidiabetic drugs consumed long-term can cause side effects; therefore, alternative treatment is needed using herbal medicinal plants. Saponins in plants are a complex class of complex natural compounds with a large molecular mass, namely steroid or triterpenoid aglycones with one or more sugar/glycoside chains. Saponins function as antioxidants. This study aims to determine the effect of saponins as one of the antioxidants on the testicular organs of rats (Rattus norvegicus) Wistar strain-induced Streptozotocin. Methods: This study used the Literature Review method with a narrative literature review type. The data collection technique uses a search for several research databases through Google Scholar and Mendeley. This research has four journals that will review. Results: The results showed that herbal plants have bioactive compounds such as flavonoids, alkaloids, terpenoids, tannins, and saponins that have antidiabetic effects with different mechanisms in reducing blood glucose levels repairing damage to testicular tissue of diabetes mellitus rats. Conclusion: Antioxidant saponins in herbal plants influence improving and supporting the repair of testicular histology damage in diabetic cases. Allah SWT grows a wide variety of plants that have enormous benefits for humans, including food and medicine, because Allah SWT created various kinds of plants with multiple uses.
The Effect of Course Schedule Density and Assignment Frequency on Burnout Syndrome in Students of The Faculty of Medicine YARSI University in 2019 And 2020 and Their Review According to Islam Rostiana, Ajeng Nita; Rahmah, Nunung Ainur; Royhan, Aan; Arifandi, Firman
Junior Medical Journal Vol. 2 No. 2 (2023): Oktober 2023
Publisher : Fakultas Kedokteran Universitas YARSI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33476/jmj.v2i2.3009

Abstract

Background: Burnout syndrome is a measure of physical exhaustion and mental stress that is driven primarily by pressure and job requirements. The academic demands experienced by medical students, such as busy class schedules, practicum materials, group discussions, clinical skills, final exams, to organizational activities are some of the factors that make the duties and obligations as students pile up, triggering to the Burnout syndrome. According to the Islamic view, patience and trustworthiness are a way to deal with fatigue in studying. Method: This type of research is quantitative which is done in an analytical observational manner with a cross sectional design. Questionnaires were distributed via Google form to YARSI University Medical Faculty students in 2019 and 2020. The sample in this study was 224 respondents. The statistical test uses the Chi-Square test. Results: In the study it was found that there were 125 (55%) students who had moderate burnout syndrome. Based on the results of statistical tests, there is no effect between schedule density and the frequency of assignments on burnout syndrome. Conclusion: There is no effect of the density of schedules and the frequency of assignments on burnout syndrome
Literature Review : Effect of Herbal Plant Extracts Containing Tannins on Histopathological Kidney of Diabetic Rats riza, salim; Etty Widayanti; Aan Royhan
Junior Medical Journal Vol. 2 No. 3 (2023): November 2023
Publisher : Fakultas Kedokteran Universitas YARSI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33476/jmj.v2i3.3317

Abstract

Hyperglycemia is a disorder of carbohydrate metabolism characterized by high blood glucose levels. Hyperglycemic treatment is usually done by administering oral hyperglycemic drugs. Therapy using drugs, either in the form of oral anti-diabetic drugs, insulin therapy, or a combination of both. Herbal medicine can be an alternative treatment in the treatment of hyperglycemia. Various types of extracts from various parts of several medicinal plants have been tested for hyperglycemic activity, one of which is due to the content of tannin compounds. The purpose of this study was to determine the effect of herbal plant extracts containing tannins on the histopathological of the kidneys of diabetic rats. The research method uses the Literature Review method with secondary data collection from scientific research articles from 2019-2023. Search data using the online Google Scholar database using key words such as tannins, diabetes, histopathology, kidney and rats. Articles are then evaluated based on the title and abstract. From the 5 results of this Literature Review, all literature states that there is an effect of herbal plant extracts containing tannins on the histopathological  of the kidneys of diabetic rats.
Hubungan Jenis Kelamin, Usia, Durasi Duduk dan Posisi duduk Pada Pembelajaran Luring Dengan Keluhan Low Back Pain (LBP) Pada Guru SMP Di Kabupaten Bogor nadila, alya; Royhan, Aan; Zen, Irwandi
Junior Medical Journal Vol. 2 No. 4: December 2023
Publisher : Fakultas Kedokteran Universitas YARSI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33476/jmj.v2i4.3978

Abstract

ABSTRAK Latar Belakang: Low Back Pain (LBP) ditandai dengan rasa nyeri di punggung bawah, pada daerah tulang belakang, otot, saraf, atau struktur lain di daerah tersebut. Sekitar 40,5% penyakit yang diderita berhubungan dengan pekerjaan. Selama pembelajaran luring, seorang guru melakukan pekerjaannya mengajar di depan kelas dengan posisi duduk duduk, berdiri ataupun berjalan selama 4-6 jam sehari, sehingga beresiko menderita LBP. Tujuan: Mengetahui hubungan jenis kelamin, usia, posisi duduk dan durasi duduk guru SMP di Kabupaten Bogor pada pembelajaran luring dengan keluhan Low Back Pain. Metode: Penelitian ini dilakukan di Kabupaten Bogor, dengan sampel sebanyak 92 orang. Analisis data dengan analisis bivariat (Chi-Square). Hasil: Keluhan LBP pada guru SMP di Kabupaten Bogor pada pembelajaran luring berhubungan erat dengan faktor usia (p=0,042) dimana guru dengan usia >40 tahun lebih banyak mempunyai keluhan ini. LBP juga berhubungan erat dengan posisi duduk yang kurang tepat (p=0,009) dan durasi duduk yang lama (>6 jam) (p=0,001). Kesimpulan: Keluhan LBP pada guru SMP di Kabupaten Bogor pada pembelajaran luring dipengaruhi oleh faktor usia, posisi duduk dan durasi duduk. Low Back Pain (LBP) adalah kondisi yang membutuhkan waktu lama untuk berkembang dan bermanifestasi. Durasi mengacu pada waktu yang dibutuhkan seorang pekerja untuk terpapar faktor risiko. Pekerjaan yang membutuhkan otot atau gerakan yang sama untuk digunakan dalam jangka waktu yang lama meningkatkan potensi kelelahan lokal dan umum. semakin lama durasi kerja, semakin lama pemulihan otot dan waktu istirahat. KATA KUNCI Low Back Pain, guru, pembelajaran luring
Literature Review: of The Effect of Plant Extracts That Contain Alkaloids on The Histopathology of Diabetic Rat Kidneys Fauzan, Muhamad Adam; Widayanti, Etty; Royhan, Aan
Junior Medical Journal Vol. 3 No. 4 (2025): Juni 2025
Publisher : Fakultas Kedokteran Universitas YARSI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33476/jmj.v3i4.3316

Abstract

Introduction: Diabetes mellitus (DM) is a chronic disease that occurs when the pancreas cannot produce enough insulin or the body cannot use the insulin made effectively. Antidiabetic drugs usually have side effects such as nausea and anorexia. Therefore, alternative medicines such as herbal medicines are needed. Plants have phytochemical compounds and secondary metabolites such as phenols, alkaloids, steroids, glycosides, flavonoids and certain pigments. Alkaloids are secondary metabolite compounds in many plant and animal tissues and have the most nitrogen atoms. This study aims to determine the research results on the effects of giving herbal plant extracts on the histopathological picture of the kidneys of diabetes mellitus rats. Methods: This study uses the Literature Review method with a narrative literature review type. Data collection techniques in this study were carried out by searching for data through the database on Google Scholar. Four journals were obtained as research sources based on the exclusion and inclusion criteria. Results: Plants that contain alkaloids are effective in improving kidney conditions. Alkaloids are antioxidant compounds that can provide nephron cell protection and kidney repair in glomerular endothelial cells, increasing the glomerular filtration rate (GFR). Increased GFR will reduce creatinine and uranium levels in the blood. Conclusion: Plant extracts that contain alkaloids can repair kidney damage in diabetes mellitus rats. According to the Islamic view, alkaloids can improve the condition of damaged kidneys, so it is allowed to consume because plants have many benefits that are very useful for human health that can be used as natural medicines.
Co-Authors Amsaka, Azha Azzuna Annisa Azzahra, Annisa Arifandi, Firman Diniwati Mukhtar Endy Muhammad Astiwara Etty Widayanti Etty Widayanti Etty Widayanti, Etty Fauzan, Muhamad Adam Harliansyah, Harliansyah Irmawati PA, Ikke Jean Kharismatik Persada Kananta, Annisa Nur Azzahra Maharsi, Dian Marsiati, Himmi Muhammad Arsyad Mustofa, M Samsul nadila, alya Nunung Ainur Rahmah Pd, Fanny Ratnasari Ridwan, Karina Ajeng riza, salim Rostiana, Ajeng Nita Salma Azizah, Jihan Samsul Mustofa, Muhammad Susmiarsih Panjiasih, Tri Yenni Zulhamidah, Yenni Yusnidar, Amirah Zen, Irwandi