This study aims to analyze the effect of regional expenditure on economic growth in Mimika Regency. The research used comparative causal method, which intended to measure the effect or investigate the effects caused by the independent variable (regional expenditure) to the dependent variable (economic growth). Data collected by interview techniques, literature study and documentation. To determine the effect of regional expenditure on economic growth in Mimika Regency, a simple linear regression analysis tool is occupied. The results showed that there was no significant correlation between regional expenditure and economic growth.. Bivariate Person correlation analysis results show r-count value (0.371)