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Slamet Suyono
Department of Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta
Medicine & Pharmacology

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The outcome of pregnancy among Graves women treated with PTU Mukhsin, Ali I.; Waspadji, Sarwono; Subekti, Imam; Soegondo, Sidartawan; Ranakusuma, Asman B.; Suyono, Slamet
Medical Journal of Indonesia Vol 9, No 4 (2000): October-December
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (822.657 KB) | DOI: 10.13181/mji.v9i4.623

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Interleukin-10 serum level in acute coronary syndrome patients Alwi, Idrus; Santoso, Teguh; Suyono, Slamet; Sutrisna, Bambang; Kresno, Siti B.
Medical Journal of Indonesia Vol 18, No 3 (2009): July-September
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (377.652 KB) | DOI: 10.13181/mji.v18i3.358

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Aim To compare plasma IL-10 concentrations in patients with Acute Coronary Syndrome (ACS) with those in Coronary Artery Disease (CAD).Methods ACS patients hospitalized in intensive coronary care unit (ICCU) of Cipto Mangunkusumo Hospital/Faculty of Medicine University of Indonesia (CMH/FMUI), Persahabatan Hospital, MMC Hospital, and Medistra Hospital, Jakarta, between May 2005 and May 2006, were included in this study. The ambulatory CAD patients were taken as comparator. The serum IL-10 level was measured by immunoassay method, and compared by using Independent Student’s t-test. To investigate whether IL-10 serum level could predict ACS, the sensitivity and specificity of this parameter towards ACS in various IL-10 serum levels were calculated as well.Results In this observational study, as many as 146 subjects were analyzed, consisting of 84 ACS patients, and 62 coronary artery disease (CAD). The IL-10 level was higher in the group of ACS patients (7.37 pg/mL + 7.81, CI 95% 5.68-9.07) than that in CAD patients (1.59 pg/mL + 1.55, CI 95% 1.2-1.98). The optimal cut-off point for serum IL-10level is >1.95 pg/mL, with 79.76 % sensitivity and 77.42 % specificity.Conclusion The IL-10 level was higher in the ACS patients compared to that in CAD patients. Serum IL-10 measurement is a quite superior method to distinguish acute and stable condition, eventhough it is not as good as hsCRP for the same purpose. (Med J Indones 2009;18:165-9)Key words: Interleukin-10, acute coronary syndrome
Co-Authors A.A. Ketut Agung Cahyawan W Ali I. Mukhsin Alida R Harahap, Alida R Asman B. Ranakusuma Bambang Sutrisna Idrus Alwi Lukman H Makmun Pradana Soewondo Sarwono Waspadji Sidartawan Soegondo Siti B. Kresno Suwignyo .