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All Journal Journal of Tropical Life Science : International Journal of Theoretical, Experimental, and Applied Life Sciences
Akhmad Darmawan
Research Center for Chemistry, Indonesian Institute of Sciences (LIPI), Kawasan PUSPIPTEK, Serpong, Tangerang Selatan, Banten, 15314
Agriculture, Biological Sciences & Forestry Environmental Science

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Apigenin, an Anticancer Isolated from Macaranga gigantifolia Leaves Sofa Fajriah; Megawati Megawati; Akhmad Darmawan
Journal of Tropical Life Science Vol. 6 No. 1 (2016)
Publisher : Journal of Tropical Life Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jtls.06.01.02

Abstract

Apigenin, a flavonoid compound has been isolated from the ethyl acetate fraction of methanol extract of Macaranga gigantifolia leaves. Isolation and purification of apigenin conducted using chromatographic method, and chemical structure characterized based on spectroscopic data. In vitro anticancer activity test against murine leukemia P-388 cell line showed potential activity with IC50 14.13 μg/mL.Key words: apigenin, flavones, Macaranga gigantifolia, anticancer, murine leukemia P-388 cell line.
Co-Authors Megawati Megawati Sofa Fajriah