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All Journal International Journal Of Science, Technology & Management (IJSTM)
Anayanti Arianto
Department Of Pharmaceutical Technology, Faculty Of Pharmacy, Universitas Sumatera Utara, Jl. Tri Dharma No. 5, Kampus USU, Medan, Sumatera Utara, Indonesia 20155
Aerospace Engineering Agriculture, Biological Sciences & Forestry Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Earth & Planetary Sciences Education Electrical & Electronics Engineering Energy Engineering Industrial & Manufacturing Engineering Mechanical Engineering Transportation

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Antibacterial Activity and Determination of Total Phenol and Flavonoid of Carica papaya L. Ethanol Extract Sry Ulina Karo-Karo; Anayanti Arianto; Emil Salim
International Journal of Science, Technology & Management Vol. 4 No. 1 (2023): January 2023
Publisher : Publisher Cv. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46729/ijstm.v4i1.738

Abstract

Infectious diseases are Indonesia's most common. Antibiotics are used to treat infections. Medicine needs new antibiotics due to antibiotic resistance. Antibiotics from plants are possible. Papaya leaf carpain alkaloids may be antibacterial. This study determined papaya leaf compound content, flavonoids' total phenol content, and the optimal concentration of papaya leaf ethanol extract that inhibits Staphylococcus aureus and Pseudomonas aeruginosa. The first stages of the research were the maceration of papaya leaf extract with 96% ethanol solvent, the phytochemical screening test (alkaloid, flavonoid, saponin, tannin, and steroid and triterpenoid tests), total phenol and total flavonoids tests, and the paper disc antibacterial activity test. Alkaloids, flavonoids, glycosides, tannins, steroids, and saponins were found in papaya leaf ethanol extract. Papaya leaf ethanol extract has 59.05 mgQE/g flavonoids and 56.80 GAE/g phenols. The antibacterial activity test of papaya leaf ethanol extract measured the diameter of the inhibitory zone on Staphylococcus aureus and Pseudomonas aeruginosa. Alkaloids, flavonoids, glycosides, tannins, steroids, and saponins were found in papaya leaf ethanol extract. Papaya leaf ethanol extract has 59.05 mgQE/g flavonoids and 56.80 GAE/g phenols. Papaya leaf ethanol extract had the best inhibition zone diameter for Staphylococcus aureus at 150 mg/mL (12.85 mm) and Pseudomonas aeruginosa at 150 mg/mL (13.10 mm).
Phytochemical Screening of Cinnamon Bark (Cinnamomum burmanii) (C. Ness & T. Ness) C. Ness ex Blume Ethanol Extract and Antioxidant Activity Test with DPPH (2,2-diphenyl-1-picrylhydrazyl) Method. Tri Susanti Sirait; Anayanti Arianto; Aminah Dalimunthe
International Journal of Science, Technology & Management Vol. 4 No. 1 (2023): January 2023
Publisher : Publisher Cv. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46729/ijstm.v4i1.739

Abstract

Cinnamon (Cinnamomum burmanii) is one of the spices that can be used as cosmetic preparations in the pharmaceutical industry because it contains potent antioxidants. Examples of cosmetic products containing cinnamon are body scrubs, body showers, and moisturizers. This study aimed to determine the antioxidant activity of cinnamon extract using the DPPH method. Cinnamon was extracted using the maceration technique with 96% ethanol solvent, and phytochemical screening was carried out. The results of phytochemical screening from cinnamon bark extract were alkaloids, saponins, tannins, triterpenoids, and flavonoids. Antioxidant activity obtained an IC50 value of 25.35 ppm. Based on these results, the cinnamon extract has a very strong antioxidant activity value.
Antibacterial Activity Of Lime Peel (Citrus Aurantifolia (Christm.) Swingle) Ethanolic Extract Against Skin Infection Bacteria (Propionibacterium Acnes And Staphylococcus Epidermidis) Novia Sormin; Anayanti Arianto; M. Pandapotan
International Journal of Science, Technology & Management Vol. 4 No. 4 (2023): July 2023
Publisher : Publisher Cv. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46729/ijstm.v4i4.841

Abstract

The skin is the outermost part of the body that serves as a protective body. In addition to protecting the skin of the face, it also acts as a beautifier. The main problem with facial skin is inflammation of the skin, which can cause acne. Bacteria like Propionibacterium acnes, Staphylococcus aureus, Staphylococcus epidermidis, and Pseudomonas aeruginosa can cause acne on the face. Prolonged use of antibiotics as therapy against acne will cause a new problem, namely resistance to antibiotics. Lime peel has many uses, especially as an antibacterial, which makes it a good candidate for use as an antibacterial agent in acne treatment. The goal of this study was to find out if the etTMhanolic extract of lime peel could kill bacteria like Propionibacterium acnes and Staphylococcus epidermidis. The research method used the Kirby-Bauer method and the Streaking methods to analyze the minimum inhibitory concentration and minimum bactericidal concentration. The results showed MIC at a concentration of 1 mg/mL for each bacterium, while MBC at a concentration of 40 mg/mL in Propionibacterium acnes and 50 mg/mL in Staphylococcus epidermidis. The conclusion is that the extract of lime peel in ethanol can kill bacteria.
Co-Authors Aminah Dalimunthe Emil Salim M. Pandapotan Novia Sormin Sry Ulina Karo-Karo Tri Susanti Sirait