Article Per Year (5 Year)
p-Index From 2021 - 2026
0
P-Index
This Author published in this journals
All Journal Journal of Global Pharma Technology
Zainab B Hashim
Unknown Affiliation
Medicine & Pharmacology

Published : 1 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search
Journal : Journal of Global Pharma Technology

 1 
Synthesis of New γ-Lactam Derived from 3-Chlorobenzo [b] Thiophene and Evaluation of Anti Bacterial Activity Zainab B Hashim
Journal of Global Pharma Technology Volume 10 Issue 06: (2018) June 2018
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

New hetero cyclic, compounds derived from cinnamic acid was synthesized. 3-Chlorobenzo[b]thiophene-2-carbonyl (Z1) was synthesized from cinnamic acid and thionyl chloride . Carbohydrazide (Z2) was obtained by the reaction of 3-Chlorobenzo [b]thiophene-2-carbonyl chloride (Z1) with hydrazine hydrate. treatment of (Z1)with ethylene di amine to give  (Z3) .(Z2,Z3) undergo condensation reaction with different aromatic aldehyde in absolute ethanol gave the Schiff′s bases (Z4-Z19) new γ- lactams (Z20- Z35)  derivatives have been synthesized by reacting of succinic anhydride with Schiff’s bases These compounds were evaluated of the anti- bacterial activitiesKeyword: benzo[b]thiophene, γ- lactams, Schiff′s bases.
Co-Authors