Communication and information technology in the world of education is an effort made in creating a different teaching-learning atmosphere so that students can develop their potential. E-Learning is a learning process that utilizes computer technology, computer networks, and the Internet in the process of disseminating knowledge, thus enabling students to learn via computers anywhere without having to physically go to class/lectures. Atma Jaya Makassar University already has an E-Learning system but several obstacles occur starting from a less interactive display, limited functions, no integration with the academic system, and the unavailability of mobile-based E-Learning. Previously, e-learning used a claroline base which had problems in terms of appearance and functionality. This research uses the SDLC (Software Development Life Cycle) method in developing e-learning software. The waterfall method is a work method that emphasizes sequential and systematic phases. This method starts from identifying the problems that occur, the design, implementation, testing and verification stages. Moodle-based E-Learning products offer to enter the "digital classroom" to access learning materials with a more attractive appearance and easier access with the mobile application version. The advantages of Moodle include being able to create learning materials, quizzes, and online discussion forums in an E-Learning package. Therefore, this study aims to improve the quality of learning will develop a moodle-based E-Learning system at Atma Jaya University Makassar.