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Sri Wardani, Ni Wayan
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Journal : Medica Hospitalia

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Besar Risiko Status Nutrisi terhadap Morbiditas dan Mortalitas Pasien Hemodialisis Reguler: Risk of Nutritional Status with Morbidity and Mortality of Regular Hemodialysis Patients Sri Wardani, Ni Wayan
Medica Hospitalia : Journal of Clinical Medicine Vol. 9 No. 2 (2022): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (354.318 KB) | DOI: 10.36408/mhjcm.v9i2.753

Abstract

Latar belakang : Protein energi wasting (PEW) merupakan salah satu komplikasi pasien yang menjalani hemodialisis (HD) reguler akibat malnutrisi dan inflamasi dan menjadi indikator mutu layanan HD. Penelitian ini bertujuan untuk menganalisis besar risiko status nutrisi terhadap morbiditas dan mortalitas pasien HD reguler. Metode : Penelitian kohort prospektif selama 6 bulan (5 Mei sampai 4 November 2021), pada pasien HD reguler, berusia lebih dari 18 tahun di unit HD RSUD Sanjiwani Gianyar. Status nutrisi dinilai dengan Indeks Massa Tubuh (IMT), kadar albumin serum, Subjective Global Assesement (SGA), Malnutrition inflammation score (MIS), dan International Society of Renal Nutrition and Malnutrition (ISRNM). Hasil : Subyek penelitian adalah 111 orang terdiri dari 61.3% laki-laki, rerata umur 53,67 tahun, rerata lama menjalani HD 44,56 bulan dengan etiologi utama yaitu hipertensi dan DKD 54%. Rerata IMT 23,41 kg/m2 dan albumin 4,05 g/dL. Analisis risiko relatif (RR) menunjukkan albumin <3,8 g/dL meningkatkan risiko morbiditas 3,25 kali (CI 95% 1,29- 8,13) p=0,01, dibandingkan albumin >/= 3,8 g/dL. Demikian juga SGA B dan C meningkatkan morbiditas 3,2 (CI 95% 1,36–7,52) kali dibandingkan SGA A dengan p=0,007, tetapi IMT, MIS dan ISRNM tidak bermakna. Analisis Kaplan Meier, menunjukkan subyek dengan status nutrisi baik mempunyai ketahanan hidup lebih lama dibandingkan dengan status nutrisi kurang, tetapi tidak bermakna secara statistik. Simpulan : Status nutrisi kurang berdasarkan albumin dan SGA signifikan meningkatkan risiko morbiditas namun tidak meningkatkan risiko mortalitas. Parameter status nutrisi lain seperti IMT, MIS, dan ISRNM bukan faktor risiko morbiditas dan mortalitas pasien HD.
Comparison of Protein Energy Wasting Assessment on Quality of Life Regular Hemodialysis Patients Sri Wardani, Ni Wayan; Budiasa, Dewa Gde Agung
Medica Hospitalia : Journal of Clinical Medicine Vol. 11 No. 2 (2024): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36408/mhjcm.v11i2.1075

Abstract

Background. Protein energy wasting (PEW) is one of several markers of the quality of hemodialysis (HD) services in Indonesia, however not many studies conducted PEW assessement with quality of life (QoL) domain of regular HD patients. Aim: To determine comparison of PEW assessment with QoL domains in regular HD patients. Method: A Cross-sectional study with total sampling of 105 regular HD patients at Sanjiwani Gianyar General Hospital, on June to July 2022, The PEW assessments: body mass index (BMI), serum albumin, subjective global assessment (SGA), malnutrition inflammation score (MIS), and the International Society of Renal Nutrition and Malnutrition (ISRNM) with QoL domains by KDQOL-SF (Kidney Disease Quality of Life Short Form). Results.  Most of the subjects were men (54.2%), the mean age was51.66 years and mean duration of HD was 50.28 months. The mean of BMI, serum creatinine, and serum albumin were 23.46 kg/m2, 9.70 mg/dL, and 3.86 mg/dL respectively, and median MIS 5. This study obtained significant correlation of BMI and QoL domains: work status, physical functioning, role of physics, energy/fatigue, and SF 12 physical composite. The MIS also significantly correlated with emotional well-being, sleep, and burden of disease. And ISRNM significantly correlated with energy/fatigue, and sexual function, On logistic regression analysis, this study obtained that albumin was significantly related to general health, emotional well-being, and energy/fatigue, Conclusion: Assessment of PEW (BMI, serum albumin, MIS, SGA, and ISRNM ) were related to several domains of QoL.
Co-Authors Asmara, Dewa Wedha Budiasa, Dewa Gde Agung Gideon, Adolf