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Journal : Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)

A Correlational Study Elevated Risk of Cardiometabolic Illness and the Prevalence of Obstructive Sleep Apnea Among the Population of Tebing Tinggi, North Sumatra, Indonesia Raynaldo, Abdul Halim; Pase, Muhammad Aron; Ketaren, Andre Pasha
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 5 No. 3 (2023): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/jetromi.v5i3.14330

Abstract

Background: Obstructive Sleep Apnea (OSA) is a prevalent sleep-related breathing issue, marked by repeated full or partial blockages of the upper airways. It's a primary respiratory condition that heightens the chances of cardiometabolic diseases. In our research, we explored the link between the increased risk of cardiometabolic ailments and the potential for OSA. Method: We studied 75 participants during community service activities and investigated the association between the high risk of cardiometabolic disease and the risk of OSA in the Society of Tebing Tinggi. We measured variables such as gender, age, weight, height, Body Mass Index (BMI), blood pressure, heart rate, random blood glucose, waist and neck circumference, and total cholesterol. Subsequently, we categorized the data and performed chi-square tests to analyze the associations between various factors and the risk of OSA. Variables with p<0.05 are considered eligible for multivariate analysis using binary logistic regression. Results: We identified 42 patients had a high risk of OSA (59.2%), while 33 patients had a low risk (40.8%). The study identified significant links between OSA risk and gender, age, blood pressure, and neck circumference (p-values <0.001, <0.001, and 0.01 respectively). In contrast, BMI, heart rate, glucose levels, waist size, and cholesterol did not show a significant connection to OSA risk. This indicates that while certain factors like gender, certain age groups, hypertension, and neck size are important in assessing OSA risk. However, BMI, heart rate, random blood glucose, waist circumference, and total cholesterol are not significant factors in determining the risk of OSA (p=0.2, p=0.4, p=0.2, p=0.1, p=0.9). Conclusions: Higher risk of cardiometabolic diseases (older age, gender, hypertension, neck size) was positively associated with the risk of OSA.
ASSOCIATION OF TRIGLYCERIDE / HIGH-DENSITY LIPOPROTEIN RATIO (TG/HDL RATIO) TO SPECIFIC RISK FACTORS OF DIABETES AND PREDIABETES Nasution, Melati Silvanni; Pase, Muhammad Aron; Nasution, Ali Nafiah
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 6 No. 4 (2024): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/jetromi.v6i4.17394

Abstract

Background: Diabetes is a group of metabolic diseases characterized by hyperglycemia due to defects in insulin secretion, insulin action, or both. Prediabetes is a precursor before the diagnosis of diabetes. Patients with prediabetes and diabetes have several risk factors, one of which is dyslipidemia. The TG/HDL ratio is found to be positively associated with insulin resistance and CVD. This study was conducted to determine whether there is a relationship between TG/HDL ratio and the incidence of prediabetes and diabetes. Method: This analytic cross-sectional study was conducted on July-December 2023. The study samples were prediabetic and diabetic patients who met the acceptance criteria of the study subjects. They were tested for BMI, BG, HbA1C and lipid profile. Data analysis used paired t test and Pearson correlation Result: In this study, BMI was greater in the prediabetes group than the diabetes group. There was a negative correlation between age, BG and HDL levels on TG/HDL ratio in prediabetic and diabetic patients. There was a significant relationship between fasting BG, 2 hours after meals BG, HbA1C and TG/HDL ratio when compared between the prediabetes and the diabetes group. Conclusion: In this study, there was no association between TG/HDL ratio in prediabetes and diabetes. Keywords: Prediabetes, diabetes, TG, HDL, HbA1c