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All Journal JURNAL FARMASIMED (JFM) Formosa Journal of Science and Technology (FJST) International Journal of Public Health Excellence (IJPHE) Jurnal Pengabdian Masyarakat Bangsa
Harahap, Susilawati
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Journal : Formosa Journal of Science and Technology (FJST)

 1 
Bioactive Compound Analysis and Antioxidant Activity Test on Ethanol Extract of Gotu Kola Leaves (Centella Asiatica) with Different Solvent Concentrations Harahap, Susilawati
Formosa Journal of Science and Technology Vol. 3 No. 2 (2024): February 2024
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/fjst.v3i2.8166

Abstract

Gotu kola (Centella Asiatica) contains the active ingredients alkaloids, saponins, tannins, flavonoids, steroids and triterpenoids. Three bioactive groups, namely triterpenoids, steroids and saponins, are antioxidants that are beneficial for the health of the human body. The aim of this research is to identify the phytochemical content, total flavonoid content and antioxidant activity in gotu kola (Centella Asiatica) leaves with different solvent concentrations. The type of research is Qualitative and Quantitative with an Experimental laboratory research design carried out at the Itkessu Pharmaceutical Laboratory. The results of the phytochemical screening identified that pegagan (Centella Asiatica) leaves were positive for containing alkaloids, flavonoids, steroids, triterpenoids and saponins at both solvent concentrations. The UV-Vis results showed that the total flavonoid content in gotu kola (Centella Asiatica) leaves was 31.6271 mg QE/Gr for 70% ethanol and 21.7821 mg QE/Gr for 96% ethanol, while the IC50 value was 53.2210 ppm for 70% ethanol and 61.7269 ppm for 96% ethanol.
Analysis of Rhodamin B in Lipstick Preparations in Padangsidimpuan City by Thin Layer Chromatography (TLC) Method Harahap, Susilawati; Lubis, Lathipah Hannah; Harahap, Minah Iryanti
Formosa Journal of Science and Technology Vol. 3 No. 8 (2024): August 2024
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/fjst.v3i8.10754

Abstract

Rhodamin B is a synthetic dye in the form of a crystalline powder, green or reddish-purple, odorless, and in solution will be bright red with fluorescence or fluorescence. Rhodamin B is commonly used as a dye in the textile and papermaking industries. Rhodamin B can cause irritation in short-term exposure and has carcinogenic effects. This study aims to find out whether there is Rhodamin B in lipsticks circulating in the Padangsidimpuan City market. Samples were taken by purposive sampling and 5 red samples were obtained. To identify the presence of Rhodamin B, a thin-layer chromatography method was used using eluene as the phase of motion, namely methanol, ethyl acetate, ammonia (50:20:25) and a 254 nm UV lamp The results of the study showed that out of 5 lipstick samples identified, there was one lipstick sample that was identified as containing Rhodamin B.
Co-Authors Harahap, Fitri Oma Ito Harahap, Fitri Omaito Harahap, Ichrima Askuri Nabella Harahap, Ickrima Azkuri Nabella Harahap, Minah Iryanti Lubis, Lathipah Hannah Nasution, Siska Futri Siska Futri Nasution