This research aims to analyze the role of Hexa Helix actors in the development of sustainable tourism at the Lejja Hot Springs Natural Tourism Park destination, South Sulawesi Province. Tourism development pays attention to the basics of sustainable tourism. This research uses a descriptive qualitative approach with a case study research design. The informants used consisted of key informants and main informants, each of whom was taken from the Hexa Helix actor. Determining informants used a purposive sampling model. Data collection methods use in-depth interviews, documentation and field observations. Data analysis used Nvivo 14 software. The research results showed that the Hexa Helix actors played a significant role in the development of natural tourism in Lejja. The government plays a role in the realm of development and empowerment policies and programs. Academics as catalysts for innovation based on research results, business units as economic facilitators, the community as actors who feel the impact of tourism development directly while carrying out monitoring functions, the media as actors who play a role in disseminating information and promotion, and visitors as actors who carry out the function of evaluating facilities and tourist destination services based on experience. In this research, cooperation between actors does not fulfill the concept of collaboration. Good cooperation between actors will speed up the tourism development process, especially in the Lejja Hot Springs Natural Tourism Park, South Sulawesi Province.