The aim of this research is to determine and analyze the influence of Work Culture on Work Commitment at the Binjai City Regional Secretariat Office. This research was conducted using a causal associative quantitative approach. The sample used was all employees with ASN status with a total of 82 people taken using proportional sampling. The research results show that Work Culture has a positive and significant effect on Work Commitment. This is shown by the T-count value of T-count of 44.054 > t table 1.66412, with a significance value of 0.000 < 0.05. The regression coefficient shows that if Work Culture is increased by 1 unit, then Work Commitment will increase by 0.957 units assuming other variables remain constant. Apart from that, the results of the determination test show an Adjusted R Square value of 0.960 or 96.00%, which indicates that Work Culture has a very high influence on Work Commitment, while the remaining 4.00% is influenced by other factors that have not been studied. Thus, partially, Work Culture has a positive and significant effect on Work Commitment at the Binjai City Regional Secretariat Office. This identifies that improvements in Work Culture can contribute to increased Work Commitment.