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Widayanti, Nurina

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Author-ID : 8015625

Civil Engineering, Building, Construction & Architecture Other

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Honey As A Treatment For Diabetic Foot Ulcer: A Systematic Review Insani, Ide Bagoes; Widayanti, Nurina; Rifki, Aliyya
Jurnal Plastik Rekonstruksi Vol. 3 No. 2 (2016): Jurnal Plastik Rekonstruksi
Publisher : Lingkar Studi Bedah Plastik Foundation

Background : Increased number of antibiotic-resistance bacteria has made honey widely reused as a modern wound treatment, including for Diabetic Foot Ulcer (DFU) treatment. Researchers have studied mean duration of wound healing and effectivity of honey dressing compared to other substances, such as povidone iodine, normal saline or alginate. This systematic review was conducted to objectively evaluate mean duration of wound healing using topical honey dressing compared to other substances in the treatment of DFU. Method : All RCT and CCT trials were collected from 4 electronic databases using keywords “Honey”, “Honey dressing”, “Diabetic foot ulcer”, and “Diabetic ulcer”. We included all English literatures with year of publication from January 2006 to November 2016; studies comparing honey with other substances; and patients with DFUs. Qualitative assessment of these studies were scored using Jadad Scale. Result : A total of 5 studies involving 517 participants were included. None of 5 studies obtained full Jadad score in quality assessment due to lack of description on randomization method, blinding and dropouts. Three studies reported significantly shorter mean duration of wound healing in honey dressing compared to normal saline and alginate dressing. Other 2 studies reported insignificant difference compared to povidone iodine, although honey still has shorter mean duration of wound healing. Two studies reported less pain during dressing changes in honey dressing group. Conclusion : Honey dressing was superior than control group (normal saline, alginate, and povidone iodine) in reducing mean duration of wound healing in DFU patients. It was also proven to cause less pain during dressing changes. Due to high heterogeneity we are unable to carry out a meta-analysis.

Rare Expression Of Van Der Wound Syndrome: A Case Report Revisited Bangun, Kristaninta; Widayanti, Nurina; Sudjatmiko, Gentur
Jurnal Plastik Rekonstruksi Vol. 3 No. 2 (2016): Jurnal Plastik Rekonstruksi
Publisher : Lingkar Studi Bedah Plastik Foundation

Background: Van der Woude syndrome (VWS) is a rare developmental malformation, characterized by pits in the lower lip. Van der Woude syndrome is an autosomal dominant craniofacial syndrome with various expression: lower lip pits, cleft lip with or without cleft palate, syngnathia, hypoodontia, and ankyloglossia. Extra-oral abnormalities findings can be found: syndactily, corpus callosum dysgenesis, megacolon, ventricular septal defect and genital abnormality. Methods: We reported a case of 5-month-old male with rare expression of VWS: bilateral cleft lip and palate, syngnathia, lower lip pits, ptosis of upper left eyelid and macropenis. Results: We perform surgery to release the fibrous band to achieve satisfactory maximum mouth opening. Next we perform cheiloplasty and lower lip pit removal. Conclusion: Proper surgical intervention in VWS patients can improve feeding and prevent further temporomandibular complications. Careful examination of patients with cleft lip and lower lip pit should be done to avoid misdiagnosis.

Parental Age As a Risk Factor Of Children With Cleft Lip In Jakarta Population: Does Paternal Age Play A Role? Widayanti, Nurina; Sudjatmiko, Gentur; Putri, Nandita Melati
Jurnal Plastik Rekonstruksi Vol. 4 No. 1 (2017): Jurnal Plastik Rekonstruksi
Publisher : Lingkar Studi Bedah Plastik Foundation

Background: Cleft lip and palate (CL/P) is one of the most common congenital anomalies with the prevalence of 1 case for every 1000 birth. The purpose of this study is to evaluate the association between paternal and maternal age to the incidence of cleft lip with or without cleft palate. Methods: This case-control study compares data of 74 cleft lip patients who was enrolled in Gentur Cleft Foundation Foundation year 2013 to 2015 compared to those of 86 normal children. Paternal and maternal age were categorized and compared to reference age (25-29 years old). Binary logistic regression was used to assess the interaction between paternal and maternal age adjusted to several confounding factors. Results: Paternal age (PA) 18-24 year has OR 9.12 (95% CI = 2.2-36.7), PA 30-34 has OR 2.74 (95% CI =1.2-5.9), PA 35-48 has OR 5.82 (95% CI = 2.2-15.67) compared to those in the 25-29 years category. Maternal age (MA) 18-24 year has OR 4.385 (95% CI = 1.86-10.36), MA 35-48 has OR 6.58 (95% CI = 1.65-26.31) compared to those in the 25-29 years category. P-value was insignificant for MA 30-34 years. Interaction were observed in crossings between PA 18-24 with MA 18-24, PA 25-29 with MA 18-24, PA 30-34 with MA 18-24, PA 30-34 with MA 25-29, PA 35-48 with MA 30-34, and PA 35-48 with MA 35-40. Conclusion: We observed stronger association between paternal ages with CL/P compared to that of maternal age. Interactions of paternal and maternal age with high OR were found in youngest age group (18-24 years old), oldest age group (above 35 years old), and fathers who are approximately 10 years older than the mother.

Parity As A Risk Factor Of Children With Cleft Lip Widayanti, Nurina; Danila, Amira; Syohanda, Wahyu Indra
Jurnal Plastik Rekonstruksi Vol. 4 No. 2 (2017): Jurnal Plastik Rekonstruksi
Publisher : Lingkar Studi Bedah Plastik Foundation

Background: Cleft lip and palate is one of the most common congenital anomalies with the prevalence of 1 case for every 1000 birth. Nulliparity has been associated with increased of many birth defects. In contrast, multiparity has also been associated with several birth defects. Methods: This case-control study compares data from 74 cleft lip patients who was enrolled in Gentur Cleft Foundation to those of 87 normal children. The dependent variable of this study was the incidence of CL/P (cleft lip with or without cleft palate) and the independent variables were maternal parity. Binary logistic regression was used to analyze crude and adjusted OR. Nulliparous mothers were treated as the reference category. Result: Compared to nulliparous mothers, primiparous mothers has OR 1.57 (95%CI=0.78-3.2). While multiparous mothers has OR 27.54 (95%CI=3.5-216.32). P-value was insignificant for the association of primiparous mothers with CL/P Conclusion: We observe higher incidence of multiparous mothers with the incidence of CL/P compared to nulliparous mothers.

Co-Authors Bangun, Kristaninta Danila, Amira Insani, Ide Bagoes Putri, Nandita Melati Rifki, Aliyya Sudjatmiko, Gentur Syohanda, Wahyu Indra

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