KADAR PLASMA KARBAMAZEPIN PADA EPILEPSI LOBUS TEMPORAL

Astri Budikayanti,* Herlyani Khosama,** Chiswyta Chaliana,*** Melva Louisa,*** Fitri Octaviana,* Luh

Majalah Kedokteran Neurosains
Vol. 34 No. 3 Juni 2017

INTRODUCTION CARBAMAZEPINE CBZ IS DRUG OF CHOICE IN THE MANAGEMENT OF TEMPORAL LOBE EPILEPSY TLE A MOST COMMON EPILEPSY SYNDROME NEVERTHELESS ITS PLASMA LEVEL IS HARD TO BE PREDICTED DUE TO THE AUTOINDUCE NATURE OF CBZ A4001600MG DOSAGE RANGE WERE EQUAL TO 412MCGML PLASMA LEVEL OF KBZ A NUMBER OF PATIENTS ARE POSITIVELY RESPOND TO LOW DOSE OF KBZ WHILE OTHER SHOWED SIGN OF INTOXICATION PRIOR TO MAXIMUM DOSE