Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML)
Vol 24, No 3 (2018)

COMPARISON OF GLYCATED HEMOGLOBIN AND GLYCATED ALBUMIN IN TYPE 2 DM PATIENTS WITH AND WITHOUT CAD

Andini Triasti Siregar (Department of Clinical Pathology Faculty of Medicine, University of North Sumatra, Medan, Indonesia)
Nizam Zikri Akbar (Department of Cardiology and Vascular Medicine Faculty of Medicine, University of North Sumatra, Medan, Indonesia)
Burhanuddin Nasution (Department of Clinical Pathology Faculty of Medicine, University of North Sumatra, Medan, Indonesia)



Article Info

Publish Date
01 Jul 2018

Abstract

Diabetes has been associated with Coronary Artery Disease (CAD). The atherosclerosis, underlying the pathogenesis of CAD, has been activated since the early stages of hyperglycemia and accelerated with uncontrolled blood sugar level fluctuations. Therefore, sensitive glycemic markers are required to be used as a screening instrument such as a traditional glycated hemoglobin A1c (HbA1c) glycated hemoglobin marker and non-traditional Glycated Albumin (GA). This study was a cross-sectional conducted on May - July 2017 at the Adam Malik Hospital Medan. Subjects were patients with HbA1c> 7%, Hb> 10 g/dL and albumin> 3 g/dL, divided into DM+CAD and non-CAD DM groups. Sixty patients participated in this study consisting of 36 males (60%) and 24 females (40%), with a mean age of 56 years. There was a significant difference between HbA1c and GA between the non-CAD DM group and DM + CAD (p=0.001; 0.022.) Patient characteristics did not affect CAD complications in DM patients; a significant difference indicated that poor glycemic control increased the complication of CAD in patients with DM type 2. Glycated albumin examination is recommended for patients with type 2 diabetes with CAD. 

Copyrights © 2018






Journal Info

Abbrev

patologi

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Neuroscience

Description

Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) is a journal published by “Association of Clinical Pathologist” professional association. This journal displays articles in the Clinical Pathology and Medical Laboratory scope. Clinical Pathology has a couple of ...