Jurnal GIZIDO
Vol 5 No 1 (2013): Jurnal GIZIDO Edisi Mei 2013

UJI EFEKTIVITAS EKSTRAK ETANOL BERAS MERAH TERHADAP PENURUNAN KADAR GLUKOSA DARAH PADA TIKUS WISTAR (Rattus norvegicus) YANG DIBERI BEBAN GLUKOSA

Dyan R. Sukandar (Jurusan Analis Kesehatan Poltekkes Kemenkes Manado)
Immanuel G. Poernomo (Jurusan Analis Kesehatan Poltekkes Kemenkes Manado)



Article Info

Publish Date
01 May 2013

Abstract

Diabetes mellitus ( DM ) is a disease in which the body can not produce insulin ( a hormoneregulating blood glucose ) . Therefore, it would lead to increased blood sugar whenexamined . Food plays a role in the increase in blood glucose levels . Despite the fibrousfoods that contain carbohydrates , but still takes time to go through the digestive system , soit has a low glycemic index . Red rice good for diabetics because it has a lower glycemicindex than white rice . Utilization of animal experiments carried out to rule the diagnosis inthe event of food poisoning , it can be selected Wistar rats as test animals . This study aimsto determine the effectiveness of red yeast rice in lowering blood glucose levels in Wistarrats given glucose load . There is a significant result in the group treated with ethanol extractof red rice 500mg/kg and 1000mg/kg bb bb the results are within the normal range .Although the treatment with 100mg/kg body weight of rats , the results are not up to therange of blood glucose levels in the range of normal mice . This is caused by theconcentration of ethanol extract of red rice is low . This study also shows that there aredifferences in blood glucose levels significantly in each treatment group and at the time oftreatment with the vulnerable period of the 30th minute to minute 120 . Anti- diabetic effectsproduced by drug glibenclamide can be used as positive controls with normal results .Conclusion The ethanol extract of red yeast rice is effective against falling glucose levelsWistar rats were given based on the concentration of glucose load and scan times .

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Journal Info

Abbrev

gizi

Publisher

Subject

Health Professions

Description

Jurnal GIZIDO merupakan jurnal berkala ilmiah dan media publikasi dari hasil-hasil penelitian (research article) di bidang gizi, pangan dan kesehatan dengan aspek gizi masyarakat, gizi klinik, gizi institusi (food service management), pangan fungsional. Jurnal GIZIDO diterbitkan oleh Jurusan Gizi ...