Pharmacology and Clinical Pharmacy Research
Vol 4, No 3

Adverse Drug Reactions in Hospitalized-Geriatric Patients with Hypertension

Andi I. Julianti (Department of Pharmacology, Bumi Siliwangi Academy of Pharmacy, Bandung, West Java, Indonesia)
Lia Amalia (Department of Pharmacology and Toxicology, Bandung Institute of Technology, Bandung, West Java, Indonesia)
Sri Hartini (Department of Pharmacology and Toxicology, Bandung Institute of Technology, Bandung, West Java, Indonesia)



Article Info

Publish Date
06 Dec 2019

Abstract

Adverse drug reactions (ADRs) occur often in geriatric patients due to various factors which include a decrease in the physiological function and organs, nutritional deficiencies, multipathology, and polypharmacy. This study aimed to identify and analyse ADRs of hospitalized-geriatric patients with hypertension. We conducted a cross-sectional retrospective study (August 2012 to January 2013). Probability determination was calculated by the Naranjo scale. The subjects on this study were hospitalized-geriatric patients (n=86, 46.51% male, and 53.48% female). Thirty-one patients (11 men and 20 women) participated in this study by completing questionnaires to calculate ADRs probability using the Naranjo scale. The probability results were 7 probable, 8 possible, and 16 doubtful. Moreover, we observed that there were drug-related problems (DRP) during therapy, e.g., appropriate dose (59.37%), and inappropriate dose 34.37%. It can be concluded that in hospitalized-geriatric patients with hypertension, some problems related to ADRs remain existed.

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Journal Info

Abbrev

pcpr

Publisher

Subject

Medicine & Pharmacology

Description

Pharmacology and Clinical Pharmacy Research (PCPR) is an international, peer-reviewed journal, publishing original research, review, case reports, and commentaries on all aspects of pharmacology and clinical pharmacy. The journal aims to contribute to the scientific committee by publishing the high ...