Journal of Pharmaceutical and Medicinal Sciences
Vol 3 No 2 (2018): JPMS

Variasi Konsentrasi Ekstrak Mahkota Bunga Kasumba Turate (Carthamus tinctorius L.) dan Ekstrak Etanol Umbi Bawang Dayak (Eleutherine palmifolia) sebagai Imunostimulan

Yuri Pratiwi Utami (Sekolah Tinggi Ilmu Farmasi Makassar)



Article Info

Publish Date
26 Aug 2019

Abstract

Fagocytosis is a process characterized by phagocytic cells ingesting good, pathogenic foreign cells commonly carried out by macrophages. This study aimed to determine the phagocytic activity of a combination of crown extract of turate kasumba (Carthamus tinctorius L.) and dayak onion tuber extract (Eleutherine palmifolia) as immunostimulant. The study was experimental, the number of mice used in the test was 21 individuals and randomly divided into 7 groups (n = 3); K1 was given C. tinctorius extract 1% w/v; K2 was given E. palmifolia extract 2% w/v; K3 was given E. palmifolia extract 4% w/v; K4 and K5 was given syrup combination C. tinctorius and E. palmifolia extract = 1 : 2 and 1 : 4% w/v; K6 was given Stimuno®; while K7 as negative control. Phagocytic activity was carried out on the 11th day using the carbon cleaning method. The results showed that the highest phagocytic activity was shown by K4 significant (p <0.05) on K1, K2, K3, K5, K6, and K7. This shows that K4 has better immunostimulatory activity than other groups.

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Journal Info

Abbrev

jpms

Publisher

Subject

Medicine & Pharmacology

Description

The Journal of Pharmaceutical and Medicinal Sciences (JPMS) pISSN 2528-2824; eISSN 2580-328X dedicated to publish original research papers, original research notes, invited topical reviews, mini-reviews, editorial commentary and news. Medicinal resources about exchange of information and ...