The process of deterioration of fresh  sh quality begins with an enzimatis damage, one of them is katepsin.To prevent deterioration of  sh, an inhibitor can be obtained naturally from the body of  sh. The purpose of this research was to use extract of cathepsin inhibitor from cat sh for inhibit deterioration of milk sh. This researchshowed that temperature of 80 ºC was the optimum temperature for extracting inhibitor complex with inhibitoryactivity of 92,88%. Cathepsin inhibitor gave the most effective to prevent deterioration (85,29% inhibitory activity) after diluted two fold on buffer solution. Soaking with inhibitors from cat sh katepsin capable to inhibit thedeterioration of  sh quality longer than 72 hours (3 days) compared with control  sh, milk sh (soaking in buffer).Keywords : catsh, cathepsin, inhibitor, milksh
                        
                        
                        
                        
                            
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