PERITONITIS BAKTERIAL SPONTAN PADA SIROSIS HATI DAN HUBUNGANNYA DENGAN BEBERAPA FAKTOR RISIKO

Ayu Yuli Gayatri, Anak Agung
Wibawa, I Dewa Nyoman

journal of internal medicine
Vol. 7, No. 2 Mei 2006

Spontaneous Bacterial Peritonitis (SBP) is a frequent and severe complication in cirrhotic patients with ascites. It occursin 10-30% of cases and assosiated mortality rate is 20-40%. Spontaneous Bacterial Peritonitis is diagnosed base on the presence ofa Polymorphonuclear leucocyte count greater than 250/mm3 or positive monomicrobial ascitic fluid culture. The key to successfultreatment of SBP is knowledge of appropriate antibiotic regimen and an understanding of the setting in wich infection develops,particularly those individuals at high risk of infection. This study was conducted to know prevalence of SBP and to evaluatepossible risk faktors for this complication such as: severe cirrhosis (Child C), upper gastrointestinal bleeding, low protein ascites(<1g/dL) and low platelet count (<98.000/mm3). Sixty two consecutive hospitalized patients with cirrhotic and ascites were followup for manifestations of SBP. Prevalence of SBP was 30.6%. Multivariate analysis and Logistic regression showed that onlysevere cirrhosis (Child C) is the risk faktor of SBP. (OR= 5.297; 95% CI=1.036-27.079).