Aktivitas Aktivitas Enzim Alanine-Aminotransferase dan Aspartate Aminotransferase pada Tikus Putih Jantan yang Diberi Ekstrak Buah Pinang

Anak Agung Sagung Kendran
Anak Agung Gde Arjana (Fakultas Kedokteran Hewan Universitas Udayana)
Anak Agung Sagung Istri Pradnyantari

Buletin Veteriner Udayana
Vol. 9 No. 2 Agustus 2017

Areca nut is a plant of Arecaceae family, known as herbal medicine and useful as an anthelmetic treatment. The aim of this research was to determine hepar toxicity of the Areca nut extracts given to male white rats by measuring ALT and AST. The doses of extracts were 100 mg/kg, 200 mg/kg, and 400 mg/kg body weight respectively. Data were analyzed by analysis of variance. The results showed that no significant effect of ALT and AST enzymes found in the treatment groups. Betel nut extract in those concentration was not toxic in the male white rats.