A new chemosensor S8 compound from the flavon group that has been successfully synthesized. Test its ability as a chemosensor for F- anion, providing positive results that it can recognize F- anion with response to an increase in fluorescent solution. Titration of S8 solution in DMSO solvents was carried out with F- anion at various concentrations and then measurements were made on fluorometry instruments. The fluorescent titration emission spectrum shows that the S8-Fˉ host-guest interaction quantitatively in the form of LOD and kass. LOD and Kass values are 6.43 × 10ˉ4 M and 2 × 106 Mˉ1, respectively.
                        
                        
                        
                        
                            
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