Calcium, phosphor and alkaline phospatase value in bone graft calsium sulfat hemihydrate bioceramic application on animal bone defect (In Vivo Study)

Bahruddin Thalib (Department of Prosthodontic, Faculty of Dentistry, Hasanuddin University Makassar, Indonesia)
Mochammad D. Utama (Department of Prosthodontic, Faculty of Dentistry, Hasanuddin University Makassar, Indonesia)
Edy Machmud (Department of Prosthodontic, Faculty of Dentistry, Hasanuddin University Makassar, Indonesia)
Asmawati Asmawati (Department of Oral Biology, Faculty of Dentistry, Hasanuddin University Makassar, Indonesia)
Steven Winarto (Department of Prosthodontic, Faculty of Dentistry, Hasanuddin University Makassar, Indonesia)
Nur Intang (Department of Prosthodontic, Faculty of Dentistry, Hasanuddin University Makassar, Indonesia)

Journal of Dentomaxillofacial Science
Vol. 4 No. 3 (2019): (Available online: 1 December 2019)

Objective: This study aims to determine differences in the value of calcium, phosphor, and alkaline phosphatase in the blood of bone graft material which is applied to bone defectsMethods: 12 male rabbits were divided into 4 groups, then defects were made in the femur bone with a diameter of 5mm. then each group was drawn with a vulnerable blood pre-operative time, 1 week, 3 weeks, and 6 weeks after surgery.Result: Average levels of calcium, alkaline phosphate and phosphorus in all treatment groups were higher than those in the control group.Conclusion: There were differences in calcium levels in test animals using bone graft α-calcium sulphate hemihydrates bioceramic on days 7th, 21st, and 42nd post surgery.