<![CDATA[Optimization of Supercritical Fluid Extraction process with mathematical modeling is essential for industrial applications. The response surface methodology (RSM) has been proven to be a useful and effective statistical method for studying the relationships between measured responses and independent factors. Recently there are growing interest in applying smart system or artificial technique to model and simulate a chemical process and also to predict, compute, classify and optimize as well as for process control. This system works by generalizing the experimental result and the process behavior and finally predict and estimate the problem. This smart system is a major assistance in the development of process from laboratory to pilot or industrial. The main advantage of intelligent systems is that the predictions can be performed easily, fast, and accurate way, which physical models unable to do. This paper shares several works that have been utilizing intelligent systems for modeling and simulating the supercritical fluid extraction process.]]>
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