Application of Digital Anti-Coincidence Counting Method for Primary Activity Determination of 59Fe

A. Agusbudiman (Center for Technology of Radiation Safety and Metrology, National Nuclear Energy Agency, Jl. Lebak Bulus Raya No. 49, Jakarta 12440, Indonesia)
K.B. Lee (Korea Research Institute of Standards and Science, 267 Gajeong-ro, Yuseong-gu, Daejeon 34113, Republic of Korea Korea University of Science and Technology, 217 Gajeong-ro, Yuseong-gu, Daejeon 34113, Republic of Korea)
J.M. Lee (Korea Research Institute of Standards and Science, 267 Gajeong-ro, Yuseong-gu, Daejeon 34113, Republic of Korea Korea University of Science and Technology, 217 Gajeong-ro, Yuseong-gu, Daejeon 34113, Republic of Korea)

Atom Indonesia Journal
Vol 45, No 2 (2019): August 2019

As a radiopharmaceutical, the use of 59Fe is classified as a high pharmaceutical risk product. Therefore, a standard reference for activity measurement of 59Fe is necessary to ensure its metrological aspect. This paper describes an alternative method for primary activity determination of 59Fe for establishing a standard reference. The 59Fe solution was prepared using two different cocktails and measured by the 4pb(LS)-g counting system using a digital anti-coincidence counting method with emulated live-time of the extending dead-time. A final activity results at the reference time for the two samples series are (473.32± 2.55) kBq/g and (477.14 ± 2.42) kBq/g with quoted uncertainty evaluated at k = 1. The final activity was compared to the value obtained from the other two coincidence counting method and found to be in a good agreement within its uncertainty value.