Althea Medical Journal
Vol 7, No 1 (2020)

Antibacterial Effect of Curcuma zedoaria Extract on Bacillus cereus and Staphylococcus epidermidis

Vidya Indriani (Universitas Prima Indonesia, Medan)
Linda Chiuman (Universitas Prima Indonesia, Medan)
Linda Leonando Wijaya (Universitas Prima Indonesia, Medan)
Gilbert Lister (Universitas Prima Indonesia, Medan)
Lexandria Grandis (Universitas Prima Indonesia, Medan)



Article Info

Publish Date
28 Mar 2020

Abstract

Background: White turmeric (Curcuma zedoaria), a plant used traditionally for medicine, is easily obtained at a relatively cheap price in Indonesia. White tumeric contains alkaloids, phenols, saponins, glycosides, steroids, terpenoids, and other compounds; and these compounds have shown antimicrobials, antifungal, anticancer, antiallergic, antioxidant, and analgesic effects. The aim of this study was to determine the antibacterial effect of white turmeric (Curcuma zedoaria) rhizome extract on the growth of Bacillus cereus and Staphylococcus epidermidis bacteria.Methods: This was an experimental study with a Post-test Only Control Group Design. It was carried out using the disc diffusion method with six treatments, consisting of negative control (aquadest), positive control (ciprofloxacin), and the extract of white turmeric rhizome with various concentrations. Kruskal Wallis test and one way ANOVA were used to analyze the data. The results showed a statistically significant value smaller than α (0.021 <0.05), and the One Way ANOVA test had a statistically significant value (p) less than α (0.000 <0.05).Results: The results of this research showed that the extract of white turmeric (Curcuma zedoaria) inhibited the growth of Bacillus cereus and Staphylococcus epidermidis bacteria at concentrations of 25%, 50%, 75%, and 100% as shown by the diameter inhibitory zone between 10-20 mm, compared to the positive control which had >20mm.Conclusions: Curcuma zedoaria has an antibacterial effect against Bacillus cereus and Staphylococcus epidermidis. Further study is needed, exploring the effectivity of white turmeric in the animal models.

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Journal Info

Abbrev

amj

Publisher

Subject

Medicine & Pharmacology

Description

Althea Medical Journal (AMJ) is a peer reviewed electronic scientific publication journal which is published every 3 months (March, June, September, and December). Althea Medical Journal publishes articles related to research in biomedical sciences, clinical medicine, family-community medicine, and ...