Path Analysis on the Biopsychosocial Factors Affecting the Quality of Life in Patients with Breast Cancer

Dewi, Rizka Amalia
Mudigdo, Ambar
Pamungkasari, Eti Poncorini

Journal of Epidemiology and Public Health
Vol 5, No 1 (2020)

Background: Breast cancer is the most com­mon cancer among women, affecting 2.1 mil­lion women every year. Assessment of quality of life is con­sidered the most important and strong in­dicator for breast cancer outcomes. The purpose of this study was to analyze biopsychosocial factors that affect the quality of life of breast cancer patients.Subjects and Method: A cross-sectional study was conducted in the breast cancer community in Su­ra­karta, Central Java from December 2019 to January 2020. A sample of 200 breast cancer patients was selected by simple random sam­pling. The dependent variable was the quality of life of breast cancer patients. The independent var­i­ables were stadium, chemotherapy, length of diag­nosis, age, depression, coping strategies, social net­­­­works, level of knowledge, education level, income level, employment status, and marital sta­­­tus. Quality of life was measured by WHO-QOL-BREF. Other data were collected by question­naire. Data were analyzed by path ana­lysis using the Stata 13 application.Results: The quality of life of breast cancer pa­tients was directly increased by high family income (b=­ 3.27; 95% CI= 1.67 to 4.87; p<0.001), strong social network (b= 2.61; 95%CI= 0.96 to 4.26; p= 0.002), length of diagnosis ≥24 months (b= 2.68; 95% CI= 0.98 to 4.39; p= 0.002), good coping strategy (b= 1.65; 95% CI= 0.12 to 3.19; p= 0.034), and finish­ed chemotherapy (b=1.32; 95% CI = -0. 22 to 2.87; p= 0.093). The quality of life of breast can­­cer patients was directly decre­ased by depression (b= -2.78; 95% CI=-4.41 to -1.15; p= 0.001) and ad­van­ced stage (b=-2.43; 95% CI= -4.04 to 0.83; p=­ 0.­003). Quality of life was in­directly affected by cop­­ing strategy, marital status, chemotherapy, know­ledge, length of diag­nosis, age, employment, and education.Conclusion: The quality of life of breast cancer pa­tients is directly increased by high family in­come, strong social network, length of diagnosis ≥24 months, good coping strategy, and finish­ed chemotherapy. The quality of life of breast can­­cer patients is directly decre­ased by depression and ad­van­ced stage. Quality of life is in­directly affect­ed by cop­­ing strategy, marital status, chemothe­rapy, know­ledge, length of diag­nosis, age, employment, and education.Keywords: quality of life, breast cancer, path analysisCorrespondence: Rizka Amalia Dewi. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Central Java, Indonesia. E­mail: [e-mail].  Mobile: +62823­13­12­1768.Journal of Epidemiology and Public Health (2020), 05(01): 119-131https://doi.org/10.26911/jepublichealth.2020.05.01.12