Jurnal Kesehatan
Vol 10, No 3 (2019): Jurnal Kesehatan

Kaempferia galanga L. sebagai Anti-Inflamasi dan Analgetik

Reandy Ilham Andriyono (University of Lampung)



Article Info

Publish Date
30 Nov 2019

Abstract

Galangal (Kaempferia galanga l) is an herb that is often used in everyday life and widely used as a spice, food flavoring, and local tonic ingredients called ‘Jamu’. Galangal is a source of zinc, starch, ethyl ester, paraeumarin, borneaol, minerals, cinnamic acid, and other nutrients that are widely used in traditional medicine applications for a long time, especially in Southeast Asia. Besides that, it has medical functions, one of which is anti-inflammatory. Inflammation is a normal protective response to tissue injuries caused by physical trauma, damaging chemicals or microbiological substances. Inflammation can also be interpreted as the body's effort to activate or damage organisms that attack, eliminate irritants and regulate tissue repair. Signs of inflammation are redness, swelling, heat, and pain. Many chemical drugs are used to prevent inflammation, one of which is that modern drugs commonly used as anti-inflammatory drugs are NSAIDs (Non-Steroid Anti-inflammatory) Mechanism as an anti-inflammatory activity by elevating anti-inflammatory production IL-10, reducing pro-inflammatory IL-6 or TNF-a production, reducing the expression of iNOS and COX-2, inhibition of PG synthesis, Kaempferia galanga L also inhibits several inflammatory mediators TNF-α, IL-1β, and Nitric Oxide (NO) and angiogenesis.

Copyrights © 2019






Journal Info

Abbrev

JK

Publisher

Subject

Health Professions Public Health

Description

Jurnal Kesehatan published by Politeknik Kesehatan Tanjungkarang with professional organizations (PTGI, PATELKI, PERSAGI, PPNI, IBI, HAKLI, PAFI, PPGI). It contains writings drawn from research and non-research, critical analytical studies in health areas. This journal was first published in April ...