The research was conducted to determine the anticarcinogenic properties of ?sisik naga?(Drymoglossum piloselloides Presl.), by the microculture tetrazolium salt (MTT) assay on the human breast carcinoma dependenthormone (MCF-7) cell lines. The preliminary results showed that the ?sisik naga? extract displayed the cytotoxic effects against MCF-7 with IC50 value of 83.63µg/ml. The antioxidative activity of the extracts which could contribute to their cytotoxic properties was also studied. The ?sisik naga? extract was found to have high antioxidant activity with IC50-value of 4.229 ppm. The strong cytotoxic properties of the ?sisik naga? extract could be due to its high antioxidant activity.
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