Objective: Benign Prostatic Hyperplasia (BPH) is the most common pathological condition in man and causes Lower Urinary Tract Syndrome (LUTS). The most popular therapeutic modality for BPH is the Transurethral Resection of Prostate (TURP). This study describes the TURP outcome in BPH patients with prostate volume >75 grams compared to <75 grams Karawang General Referral Hospital. Material & Methods: We performed a retrospective review of clinical outcome from BPH patient with LUTS who underwent TURP procedure between January 2017–April 2018. Data is taken through patient medical records and processed descriptively to describe complications, quality of life, laboratory. Qualitative data compared with Chi-Square test. Results: During this study, we evaluate 40 patients, 20 patients with prostate volume >75 grams (Group 1) and 20 patients prostate volume <75 grams. Mean age in group 1 65,60 ± 9.960 and in group 2 65,35 ± 10,297. IPSS after TURP between group 1 and group 2 show a significant difference, where the Incomplete Emptying found most in group 2 (P<0,05). There is no significant difference Quality of Life Score between group 1 and group 2 (P>0,05). From laboratory result obtain decrease of mean Haemoglobin percentage in both groups with P value <0,05 in group 1 and P value <0,05 in group 2. Conclusion: TURP procedure for patient with prostate volume >75 grams is safety and effective with lower complications and there is no significant difference compared to patient with prostate volume <75 grams.
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