Green Medical Journal
Vol 1 No 1 (2019): Green Medical Journal

Ekspresi Gen P53 Pada Pterigium Primer Dan Pterigium Rekuren

Ratih Natasha (Universitas Muslim Indonesia)
Sitti Rukiyah Syawal (Universitas Hasanuddin)
Halimah Pagarra (Universitas Hasanuddin)
Arifin Seweng (Universitas Hasanuddin)



Article Info

Publish Date
01 Dec 2019

Abstract

The purpose of the present study was to identify and compare the mutant P53 expression in primary and recurrent pterygium. The method of the study was observational analytic cross- sectional study with 19 samples of primary pterygium and 19 samples recurrent pterygium. Data obtained with pterygium tissue sampling then performed with immunohistochemical examination. Results The Study was conducted for 5 month with 19 samples of primary pterygium and 19 samples of recurrent pterygium. From the overall data shown that P53 expression of primary and recurrent pterygium average 191.6 while there is 38.3 for primary pterygium and 344.8 for recurrent pterygium. There were significant differences between the expression of P53 of primary and P53 expression of recurrent pterygium with (P = 0.000). Conclusions is There was no significant difference in the mean expression of P53 according to the stage of pterygium although there was a tendency of P53 expression of getting smaller with increasing stage of pterygium.

Copyrights © 2019






Journal Info

Abbrev

gmj

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Public Health

Description

Green Medical Journal (GMJ) is a peer-reviewed, open-access journal that publishes original research articles, review articles, and interesting case reports. The journal focuses on promoting medical and health sciences, derived from basic sciences, clinical and community health research, both in ...