<![CDATA[Knee osteoarthritis is a degenerative joint disease which affects people mostly from elderly population. Knee cartilage segmentation is still a driving force in managing early symptoms of knee pain and its consequences of physical disability. However, manual delineation of the tissue of interest by single trained operator is very time consuming. This project utilized a fully-automated segmentation that combined a series of image processing methods to process sagittal knee images. MRI scans undergo Bi-Bezier curve contrast enhancement which increase the distinctiveness of cartilage tissue. Bone-cartilage complex is extracted with dilation of mask resulted from region growing at distal femoral bone. Later, the processed image is clustered with k = 2, into two groups, including coarse cartilage group and background. The thin layer of cartilage is successfully clustered with satisfactory accuracy of 0.987±0.004, sensitivity 0.685±0.065 of and specificity of 0.994±0.004. The results obtained are promising and potentially replace the manual labelling process of training set in convolutional neural network model.]]>
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