<![CDATA[Background: Hemodialysis therapy is one of the management strategies for people with chronic kidney failure. Hemodialysis therapy can affect physical, psychological, social, and economic functions, as well as aspects of the environment that affect daily life, such as fatigue. Objectives: This study aimed to determine the factors associated with the incidence of fatigue in chronic kidney disease patients who routinely undergo hemodialysis therapy. Methods: The study used quantitative analytics with a cross-sectional approach. The sampling technique used was non-probability sampling, namely purposive sampling with a sample size of 50 patients who routinely undergo hemodialysis at UMM General Hospital. Results: result of measuring the level of fatigue in patients undergoing hemodialysis with mild fatigue 17 people (34%) and severe fatigue 33% (66%), male gender 32 people (62%) more than women 18 people (36%), age ≤45 years 15 people (30%) and age >45 years 35 people (70%), as many as 40 people (80%) have comorbidities, length of hemodialysis ≤5 months 19 people (38%) less than >5 months as many as 31 people (62%). The statistical test results of the chi-square test showed that there was no correlation between gender and the incidence of fatigue (p-value=0.700), there was a correlation between age (p-value=0.021), comorbidities (p-value=0.021), duration of hemodialysis (p-value=0.015) with the incidence of fatigue. Some factors that cause fatigue in patients with hemodialysis therapy include age over 45 years, comorbidities, and length of hemodialysis.]]>
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