Journal of Physics and Its Applications
Vol 2, No 1 (2019): November 2019

Synthesis of Zn-Fe nanoparticles using pulse laser ablation as a contrast agent in magnetic resonance imaging

Nurul Hikmantiyah (Department of Physics, Faculty of Science and Mathematics, Diponegoro University)
Eko Hidayanto (Department of Physics, Faculty of Science and Mathematics, Diponegoro University)
Ali Khumaeni (Department of Physics, Faculty of Science and Mathematics, Diponegoro University)



Article Info

Publish Date
12 Dec 2019

Abstract

Synthesis of zinc oxide nanoparticles, iron oxide nanoparticles and Zn-Fe nanoparticles using pulse laser ablation method has been conducted. Experimentally, a pulse Nd:YAG laser (1064 nm, 7 ns, 35 mJ) was directed and focused on a metal plates of pure Zn and Fe, which are placed in the liquid medium of polyvinyl pyrrolidone (PVP). The PVP functions as a stabilizer agent. The results show that the produced nanoparticles have a spherical shape with an averaged diameter of Zn-Fe nanoparticles of 13 nm. FTIR and XRD test results of Zn-Fe nanoparticles show characteristics of Zn-Fe compounds. The examination of Zn-Fe nanoparticles as MRI contrast agents was carried out by varying the concentration of nanoparticles. Cenh calculation results showed the highest contrast enhancement occurred at a concentration of 1.25 mM with a value of 64.26% for T1 weighted images, and 81.52% for T2 weighted images. The SNR calculation results show the highest value at a concentration of 1.25 mM of 70.52 for T1 weighted images. The highest SNR value in the T2 weighted image at a concentration of 0.156 mM of 165.09.

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Journal Info

Abbrev

jpa

Publisher

Subject

Astronomy Earth & Planetary Sciences Materials Science & Nanotechnology Physics

Description

Journal of Physics and Its Applications (JPA) (e-ISSN: 2622-5956) is open access, International peer-reviewed journal that publishes high-novelty and original research papers and review papers in the field of physics including Radiation Physics, Materials, Geophysics, Theoretical Physics, ...