Cellulolytic bacteria has been isolated from water and sediment sample of Indragiri river waters. Cellulase was produced by cellulolytic bacterial isolates in 1% Carboxy Methyl Cellulose (CMC) liquid medium at 37°C, 150 rpm for 24 h. The specific activity of cellulase was determined by Nelson-Somogy’s method (cellulase enzyme activity) and Lowry’s method (protein concentration). 914-5 sedimen isolates showed the highest activity of the enzyme 12,246.10 -4 ± 0,5885.10 -4 U/mL from 17 other isolates that was significantly different at (P≤0,05) compared with the other isolate.
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