Jurnal Kimia Mulawarman
Vol 12 No 2 (2015)

AKTIVITAS ANTIHIPERGLIKEMIK DARI EKSTRAK ETANOL DAN n-HEKSANA DAUN KEMBANG BULAN [Tithonia diversifolia A.Gray] PADA TIKUS PUTIH JANTAN

Ary Rizki Darmawi (Jurusan KimiaFakultas Matematika dan Ilmu Pengetahuan AlamUniversitas Mulawarman)
Chairul Saleh (Jurusan KimiaFakultas Matematika dan Ilmu Pengetahuan AlamUniversitas Mulawarman)
Rudi Kartika (Jurusan KimiaFakultas Matematika dan Ilmu Pengetahuan AlamUniversitas Mulawarman)



Article Info

Publish Date
22 Sep 2015

Abstract

Phytochemical test and antihyperglicemic activity from ethanol extract dan n-hexane extract from kembang bulan (Tithonia diversifolia A.Gray) leaf has been carried out. Based on the test result of phytochemistry of secondary metabolites compounds from kembang bulan (Tithonia diversifolia A.Gray) leaf showed that ethanol extract fraction containing flavonoid, fenolik, alkaloid and saponin. Whereas at n-hexane extract fraction containing alkaloid, saponin and steroid. Antihyperglicemic activity test using the method of glucose tolerance where a white male rats got induced by sucrose. Measurement of blood sugar levels using glucometer and glucose test strip. From this test shows that the most active fractions to reduce blood sugar levels was ethanol extract with a dose of 77 mg/kg BB with percentage of blood sugar levels reduction in the amount of 54.15 % it was close with reduction percentage from acarbose as positive control in the amount of 55.57 %.

Copyrights © 2015






Journal Info

Abbrev

JKM

Publisher

Subject

Chemistry

Description

Journal of Kimia Mulawarman is a peer-reviewed, open access journal that publishes original research articles, review articles, as well as short communication in all areas of chemistry, including educational chemistry and applied ...