JURNAL MATEMATIKA STATISTIKA DAN KOMPUTASI
Vol. 17 No. 2 (2021): JANUARY 2021

Analisis Kestabilan Model Matematika Sistem Respon Inflamasi Akibat Infeksi SARS Coronavirus

Ario Wiraya (085725300550)



Article Info

Publish Date
23 Dec 2020

Abstract

Severe Acute Respiratory Syndrome (SARS) Coronavirus infection in a human body indicated by cytokine response due to an inflammation. The purpose of this research is to construct and analyze a mathematical model of interaction between inflammatory pro-response and anti-response cytokine to predict the dynamic on inflammatory response system, so that the treatment can be optimized. The results obtained in this research describe some dynamics which happen on the cytokines, i.e. the disease-free equilibrium point is asymptotically stable when the basic reproduction number is less than one. In this condition, a patient with initial concentrations of the cytokines around the disease-free equilibrium point will be free of viral infection. The infection equilibrium point is asymptotically stable when the basic reproduction number is greater than one. In this condition, a patient with initial concentrations of the cytokines around the infection equilibrium point will be infected by the virus. Probability of a patient being free of viral infection can increase if the production rate of the cytokines are decreased or the degradation rate of the cytokines are increased.

Copyrights © 2021






Journal Info

Abbrev

jmsk

Publisher

Subject

Mathematics

Description

Jurnal ini mempublikasikan paper-paper original hasil-hasil penelitian dibidang Matematika, Statistika dan Komputasi ...