Folia Medica Indonesiana
Vol. 55 No. 4 (2019): December

Correlation of Mothers with History of Diabetes Mellitus and Infants with Anti-GAD65

Salamy, Nanda Fadhilah Witris (Unknown)
Sari, Gadis Meinar (Unknown)
Purwanto, Bambang (Unknown)
Sulistiawati, Sulistiawati (Unknown)



Article Info

Publish Date
31 Dec 2019

Abstract

This study aimed to determine the relationship between mothers with history of diabetes mellitus with Infants with Anti-GAD65. This study was an observational analytic study with a cohort study design. The case studied was the relationship between maternal history of diabetes mellitus and infants with Anti-GAD65. This study was conducted at Jemursari Hospital in Surabaya. Sample examination was performed with a GAD65 autoimmune rapid test. Then, a statistical test was performed to determine its relationship with other variables. There was no relationship between mothers with history of diabetes mellitus and infants with Anti-GAD65, but there was a significant relationship between Anti-GDA65 Mothers with Infants with Anti-GAD65. Thus, there was a possibility of transplacental antibody transfer and viral infections during pregnancy that cause damage to pancreatic beta cells. History of diabetes mellitus was not related to infants with Anti-GAD65, but there was a relationship between Anti-GAD65 Mothers with Anti-GAD65 BAyi so that there is a transfer of transplacenta antibodies and viral infections during pregnancy that can cause damage to beta pancreatic cells in infants.

Copyrights © 2019






Journal Info

Abbrev

FMI

Publisher

Subject

Other

Description

Folia Medica Indonesiana publishes articles in the field of medical science in particular and health sciences in general, as well as a variety of other fields related to those two disciplines. Most of the articles are research article, and others are articles on case reports and literature review. ...