Aceh Journal of Animal Science
Vol 6, No 1 (2021): February 2021

Genotoxicity evaluation of Chlorfenapyr in exposed freshwater African catfish Clarias gariepinus using micronucleus test

Imeh Kokoete Esenowo (Animal and Environmental Biology University of Uyo Akwa Ibom State Nigeria)
Akwaowo U. Nelson (1 Department of Animal and Environmental Biology, Faculty of Science, University of Uyo)
Chibuisi G. Alimba (Cell Biology and Genetics Unit, Department of Zoology, University of Ibadan, Nigeria)
Ndifreke D. Ekpo (Unknown)
Okeh C. Emmanuel (Unknown)



Article Info

Publish Date
28 Jan 2021

Abstract

Chlorfenapyr is a new formulated insecticide targeted against insecticide resistant species. Its application in targeting harmful aquatic insects may potentially contaminate aquatic environment. This study is to evaluate its genotoxic effects on non-targeted aquatic biota. The study assessed the genotoxic potentials of chlorfenapyr in African catfish (Clarias gariepinus) using the micronucleus (MN) test. Juvenile stage of C. gariepinus were exposed to different concentrations; 5.00 – 15.00 mgL-1 of chlorfenapyr for 96 hours, peripheral blood was collected through the caudal vein and examined for micronucleus induction in the erythrocytes. The tested concentrations of chlorfenapyr did not elicit significant [F (5, 18) = 0.167, p 0.971] increase in MN formation and other nuclear abnormalities in the peripheral erythrocytes of C. gariepinus. The outcome of this study gives credence to the view that chlorfenapyr is not clastogenic and or aneugenic to non-targeted aquatic vertebrate with reference to fish (C. gariepinus).

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Journal Info

Abbrev

AJAS

Publisher

Subject

Description

Aceh Journal of Animal Science (Aceh J. Anim. Sci.) is an international peer-review journal published by Faculty of Marine and Fisheries, Syiah Kuala University in collaboration with Indonesian Society for Oceanology (ISOI) of Aceh Chapter and supported by Institute of Graduate Studies Syiah Kuala ...