Health Media
Vol 1 No 2 (2020)

The Examination activity of salam leaf ethanolic ekstract (Syzygium polyanthum)[Wight] in mice

Shinta Mayasari (STIKES dr Soebandi Jember)
Wima Anggitasari (Program Studi Sarjana Farmasi, STIKES dr Soebandi Jember Jawa Timur, Indonesia)
Nafisah Isnawati (Program Studi Sarjana Farmasi, STIKES dr Soebandi Jember Jawa Timur, Indonesia)



Article Info

Publish Date
27 Jun 2020

Abstract

The examination effect of salam leaf ethanolic extract where the purposed of this study was to determine the effect and concentration of salam leaves as antidiarrheals. Ethanol extract dosages of salam leaf given orally (mg/kgbw) was 15;20;25;30;and 35, carried out abservations on mice starting diarrhea, weight of faeces, frequency diarrhea, and the duration of diarrhea for 5 hours. Loperamide HCl given dose of 1 mg/kg is used comparison with negative control CMC-Na, and comparison of Loperamide HCl was the 56th minute, 57,3; 57,9; 59; 58; 64,3 ; 54,3. Stool weight obtained an average of 0,34; 0,35; 0,32; 0,25; 0,27; 0,53; 0,21. The frequency of diarrhea was 8,8; 8,6; 8,9; 9,3; 8,6; 11,2; 8,5. Onset of diarrheal was average of minutes was 206,8; 207,6 ; 209,2; 209; 206,2; 230 and 88. From the research results obtained ethanol extract salam leaves given antidiarrheal effects with an optimum dose of 35mg/kgbw.

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healthmedia

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Health Media adalah jurnal yang menerbitkan artikel di bidang kesehatan. mencakup kesehatan secara umum, ilmu kedokteran, kefarmasian, keperawatan, kesehatan masyarakat, kesehatan lingkungan hingga kebidanan dan cabang ilmu kesehatan terkait ...