<![CDATA[Wualae (Etlingera elatior (Jack) R. M. Smith) is plant that traditionally used as traditional medicine in Southeast Sulawesi. It contains fl avonoids, tannins, and terpenoids that act as anti-infl ammatory. The studyaims to investigate the anti-infl ammatory activity of ethanolic extract of wualae by stabilizing human red bloodcell (HRBC) membrane. Hemolysis and stability due to oxidative induction and hypotonic solutes are used asmeasures of anti-infl ammatory activity. The positive controls used in this study were diclofenac sodium withvarious concentrations of 250 ppm; 500 ppm; 750 ppm; 1000 ppm; 1250 ppm; and 1500 ppm. Sample wasalso having similar identical concentration. According to the results of stability and hemolysis percentage ofE. elatior fruit ethanol extract to HRBC were 57,75% and 42,25% (250 ppm), 66,71% and 33,29% (500 ppm),74,10% and 25,90% (750 ppm), 75,72% and 24,28% (1000 ppm), 79,87% and 20,13% (1250 ppm), and 84,89%and 15,11% (1500 ppm). Compared with diclofenac sodium stability and hemolysis percentage were 62,61%and 37,39% (250 ppm), 66,71% and 33,29% (500 ppm), 71,02% and 28,98% (750 ppm), 72,10% and 27,90%(1000 ppm), 73,94% and 26,06% (1250 ppm), 76,63% and 23,37% (1500 ppm). These data suggest that the ethanolic extract of wualae is potentially have activity as anti-infl ammatory.]]>
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