Borneo Journal of Medical Laboratory Technology
Vol 3 No 1 (2020): Borneo Journal of Medical Laboratory Technology

Review: Effect of Red Cabbage Juice (Brassica oleracea var. Capitata f. Rubra) on SGPT Level

Hesty Wahyuningsih (Universitas Islam Sultan Agung)
Andina Putri Aulia (Universitas Islam Sultan Agung)



Article Info

Publish Date
31 Oct 2020

Abstract

Red cabbage (Brassica oleracea var. Capitata f. Rubra) is a vegetable widely used in Indonesian cuisine. Red cabbage is rich in anthocyanins to reduce SGPT levels in drug-induced liver injury (DILI). This study aims to determine the effect of red cabbage juice on SGPT levels in acetaminophen-induced liver injury. In this post-test, only the control group study, male Wistar rats (300g), were randomly divided into 5 groups (K1-K2-K3-K4-K5). Acetaminophen was given to induce liver injury in rats. The rats were treated with the cabbage juice (at the dose of 0.5g/ml or 0.7g/ml or 0.9g/ ml. Data were analyzed using One way ANOVA and LSD post hoc test. Mean SGPT levels for K1, K2, K3, K4, K5 was 58.43 ± 7.18 UI / L, 71.20 ± 9.13 UI/L, 55.73 ± 9.51 UI / L, 72.80 ± 3.47 UI /L, 72.63 ± 3.01 UI /L, respectively. One way ANOVA resulted in p=0.00 (p <0.05). The post hoc LSD test showed significant differences (P <0.05) between all groups except between groups K1-K3, K2-K4, and K2-K5 (p> 0.05). Red cabbage juice can reduce SGPT in acetaminophen-induced liver injury in rats. The most effective dose was 0.5 g/ml.

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Journal Info

Abbrev

bjmlt

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology

Description

Borneo Journal of Medical Laboratory Technology is a Scientific Journal managed by Department of Medical Laboratory Technology Faculty of Health Science Universitas Muhammadiyah Palangkaraya and published twice a year (in October and April) by Institute for Researches and Community Services ...