<![CDATA[Background: It is estimated that 2% of the world's population (about 123 million people) was infected with hepatitis C. Blood transfusion is one of the therapies, but this therapy is at risk of being a transmission medium for hepatitis B infection. Hemodialysis patients are in the group at risk of having hepatitis C infection. Patients with a history of blood transfusions in this group increase the incidence of hepatitis C infection. This study aimed to determine the estimated effect of blood transfusions on hepatitis C infection in hemodialysis patients with a meta-analysis.Subjects and Method: Meta-analysis was conducted by searching for articles from databases such as Google Scholar, PubMed, Springer Link, and Research Gate. The keywords were "blood transfusion" OR "risk factor" AND "hepatitis C infection" OR "TTI" OR "HBV" AND "patient hemodialysis" OR "Patient renal failure". The inclusion criteria were full-text articles, from 2000-2020, with a cross-sectional study design. The articles were analyzed using RevMan 5.3.Results: There were 9 articles analyzed. The results showed that blood transfusions increased the incidence of hepatitis C infection in hemodialysis patients (aOR= 1.55; 95% CI= 1.19 to 2.03; p= 0.001) and I2= 90%. Based on the meta-analysis result, there was no publication bias.Conclusion: Blood transfusion affects hemodialysis patients with hepatitis C infection.Keywords: blood transfusion, hepatitis C infection, hemodialysis patientsCorrespondence: Yuli Astuti. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Central Java. Email: yuliastuti1224@gmail.com. Mobile: 083821875621Journal of Epidemiology and Public Health (2020), 05(03): 339-347https://doi.org/10.26911/jepublichealth.2020.05.03.08. ]]>
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