Tension-Type Headache (TTH) headache is a type of primary headache which mostlycomplained by patients. The pain often ignored due to low mortality rates. Inadequatemanagement makes the pain becoming chronic and causing a high disability rate. Many factorsinvolved in transforming infrequent tension-type headache to chronic tension-type headache.A deeper understanding of the immune system's role in the pathophysiological process andmodulation of chronic pain could be a potential target for developing therapies in managingchronic pain.
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